Evidence map›Paper›PMID 40088271›Full record

ArticleEuropean journal of applied physiology2025

Eccentric training effects on hamstring muscles in oral contraceptive users and naturally menstruating women.

Olivier Seynnes, Antoine Nordez, Lilian Lacourpaille, Eirik Hesseberg, Ingvild Vesterhus, Ken Fjeldberg, Martin Kvalvik Engstad, Mette Hansen, Gøran Paulsen

Abstract read
In one paragraph

Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olivier SeynnesDepartment for Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway. oliviers@nih.no.ORCID http://orcid.org/0000-0002-1289-246X
Antoine NordezMouvement - Interactions - Performance, MIP, UR 4334, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-7276-4793
Lilian LacourpailleMouvement - Interactions - Performance, MIP, UR 4334, Nantes Université, Nantes, France.ORCID http://orcid.org/0000-0002-9664-8121
Eirik HessebergDepartment for Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.
Ingvild VesterhusDepartment for Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.
Ken FjeldbergDepartment for Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.
Martin Kvalvik EngstadDepartment for Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.
Mette HansenDepartment for Public Health, Aarhus University, Århus, Denmark.ORCID http://orcid.org/0000-0002-9383-8202
Gøran PaulsenDepartment for Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.ORCID http://orcid.org/0000-0002-6350-0112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluated the effects of eccentric resistance training on hamstring muscles properties in women using oral contraceptives (OC) and naturally menstruating women.

methodsBefore and after the training intervention, we measured maximal isometric and eccentric moment of the knee flexor muscles, thickness and shear wave velocity (SWV) of the biceps femoris long head (BFlh), semitendinosus (ST) and semimembranosus (SM) muscles, and BFlh fascicle length using ultrasonography and dynamometry.

resultsThe 12-week training intervention resulted in a modest but statistically significant increase in resting BFlh fascicle length (~2% on average, p = 0.005) across both groups, with no observed effect of OC use on any variable. The muscle strength and thickness increased comparably in both groups, with an average increase of ~20% in isometric knee flexor moment and 14% in eccentric knee flexor moment (p < 0.001 for both tests). ST muscle thickness increased by ~4% on average (p = 0.016), while no main effect of training was observed for SM and BFlh thickness. The shear modulus of the SM muscle decreased by 9% (p = 0.021) for the combined groups. However, it remained unchanged in the BFlh and ST muscles, and OC use did not influence these measurements either.

conclusionThese findings suggest that eccentric training induces similar adaptations in women regardless of OC use. Furthermore, fascicle lengthening was not attributable to changes in muscle shear modulus under the present conditions.

Indexed as

Contraceptives, OralHamstring MusclesMenstruationResistance TrainingAdultFemaleHumansIsometric ContractionMuscle StrengthYoung AdultContraceptives, OralBirth control pillEstradiolEstrogenHormonal contraceptionResistance training

Identifiers

PMID40088271
PMCPMC12354606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.