Evidence map›Paper›PMID 40088092›Full record

ArticleCancer communications (London, England)2025

Comprehensive DSRCT multi-omics analyses unveil CACNA2D2 as a diagnostic hallmark and super-enhancer-driven EWSR1::WT1 signature gene.

Florian Henning Geyer, Alina Ritter, Seneca Kinn-Gurzo, Tobias Faehling, Jing Li, Armin Jarosch, Carine Ngo, Endrit Vinca, Karim Aljakouch, Azhar Orynbek and 24 more

Abstract read
In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Florian Henning GeyerHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Alina RitterHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Seneca Kinn-GurzoChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Tobias FaehlingHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Jing LiHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Armin JaroschDepartment of Pathology, Charité-University Medicine Berlin, Corporate Member of Freie Universität Berlin and Humboldt-University of Berlin, Berlin, Germany.
Carine NgoSarcoma Unit, Gustave Roussy Cancer Campus, Villejuif, France.ORCID https://orcid.org/0000-0002-8172-5876
Endrit VincaHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Karim AljakouchDivision of Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), and Heidelberg University Medical Faculty, Heidelberg, Germany.
Azhar OrynbekDivision of Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), and Heidelberg University Medical Faculty, Heidelberg, Germany.
Shunya OhmuraHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Thomas KirchnerInstitute of Pathology, Faculty of Medicine, Ludwig-Maximilian-University of Munich, Munich, Germany.
Roland ImleHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Laura Romero-PérezInstitute of Biomedicine of Seville (IBiS)/University Hospital Virgen del Rocío/CSIC/University of Seville/CIBERONC, Seville, Spain.ORCID https://orcid.org/0000-0003-3196-4382
Juan Díaz-MartínInstitute of Biomedicine of Seville (IBiS)/University Hospital Virgen del Rocío/CSIC/University of Seville/CIBERONC, Seville, Spain.
Stefanie BertramInstitute of Pathology, University Hospital Essen, Essen, Germany.
Enrique de ÁlavaInstitute of Biomedicine of Seville (IBiS)/University Hospital Virgen del Rocío/CSIC/University of Seville/CIBERONC, Seville, Spain.
Clémence HenonERC Chromatin Remodeling, DNA Repair, and Epigenetics Laboratory, ARC Team for Fundamental Research, INSERM U981, and Drug Development Department, Gustave Roussy, Villejuif, France.
Sophie Postel-VilnayERC Chromatin Remodeling, DNA Repair, and Epigenetics Laboratory, ARC Team for Fundamental Research, INSERM U981, and Drug Development Department, Gustave Roussy, Villejuif, France.
Ana BanitoHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Martin SillHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Yvonne Versleijen-JonkersDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
Benjamin Friedrich Berthold MayerDepartment of Pediatric Surgery and Pediatric Urology, University Children's Hospital, Tübingen, Germany.
Martin EbingerDepartment of Pediatric Hematology and Oncology, University Children's Hospital, Tuebingen, Germany.
Monika Sparber-SauerStuttgart University Hospital gKAöR, Olgahospital, Stuttgart Cancer Center, Center for Child, Adolescent, and Women's Medicine, Pediatrics 5 (Pediatric Oncology, Hematology, Immunology), Stuttgart, Germany.
Sabine StegmaierStuttgart University Hospital gKAöR, Olgahospital, Stuttgart Cancer Center, Center for Child, Adolescent, and Women's Medicine, Pediatrics 5 (Pediatric Oncology, Hematology, Immunology), Stuttgart, Germany.
Daniel BaumhoerBone Tumor Reference Centre, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, and Basel Research Centre of Child Health, Basel, Switzerland.
Wolfgang HartmannGerhard-Domagk-Institute of Pathology, University of Muenster, Muenster, Germany.
Jeroen KrijgsveldDivision of Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), and Heidelberg University Medical Faculty, Heidelberg, Germany.
David HorstDepartment of Pathology, Charité-University Medicine Berlin, Corporate Member of Freie Universität Berlin and Humboldt-University of Berlin, Berlin, Germany.
Olivier DelattreDiversity and Plasticity of Pediatric Tumors, Paris Sciences and Letters University, SIREDO Oncology Centre, Institut Curie, Paris, France.
Patrick Joseph GroharChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Thomas Georg Phillip GrünewaldHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Florencia Cidre-AranazHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.ORCID https://orcid.org/0000-0002-0246-7179

Funding

Barbara and Wilfried Mohr foundation DHK-70114111Cancer Research UKDeutsche Forschungsgemeinschaft DFG 458891500Dr. Leopold und Carmen Ellinger FoundationDr. Rolf M. Schwiete foundationDr. Rolf M. Schwiete Stiftung 2020-028Dr. Rolf M. Schwiete Stiftung 2022-31European Research Council ERC CoG 2023 #101122595German Academic Scholarship FoundationGerman Cancer Aid DKH-70112257German Cancer Aid DKH-7011411German Cancer Aid DKH-70114278German Cancer Aid DKH-70115315German Cancer Aid through the 'Mildred-Scheel-Doctoral Program' DKH-70114866Heinrich F.C. Behr foundationMatthias-Lackas FoundationMinistry of Education and ResearchNCI NIH HHSRudolf and Brigitte Zenner foundationScientific Foundation of the Spanish Association Against Cancer And KiKaSMARCB1 association
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40088092
PMCPMC12187571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.