ArticleEuropean journal of neurology2025
Beyond early motor response: Longitudinal cognitive and gait assessments after extended lumbar drainage in normal pressure hydrocephalus.
Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Assessment of patients affected by INPH after external lumbar drainage: what is the better timing?Fluids and barriers of the CNS · 2026Article
- Predictive Value of Digital Neuropsychological and Gait Assessments on Shunt Outcome in Patients With Idiopathic Normal Pressure Hydrocephalus: Prospective Cohort Study.Journal of medical Internet research · 2025Article
- Time Course of Symptoms in Normal-Pressure Hydrocephalus: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Beyond early motor response: Longitudinal cognitive and gait assessments after extended lumbar drainage in normal pressure hydrocephalus.European journal of neurology · 2025Article
- Challenges in neuropsychological improvement after shunt surgery for idiopathic normal pressure hydrocephalus.Frontiers in aging neuroscience · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
backgroundIdiopathic normal pressure hydrocephalus (iNPH) is a multifactorial progressive disease affecting cognition, gait, and urinary continence, potentially reversible, or at least improvable, by a prompt surgical intervention. Given its potential surgical improvement, it is crucial to determine who will benefit of a ventriculo-peritoneal shunt. To date, although several procedures are considered useful to diagnose iNPH, there is no agreement concerning the best timing of the clinical assessment or the role played by formal cognitive testing.
methodsThirty participants with suspected iNPH were assessed at baseline, 2, and 15 days after 24-h extended lumbar drainage (ELD). Timed Up and Go test (TUG), Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and Frontal Assessment Battery (FAB) were administered in order to quantify motor and cognitive performances. The TUG was used to assess clinical response to ELD.
resultsOur sample showed significant differences between baseline assessment and follow-ups in the majority of tests. Although some enhancements in performances appeared in the first post-ELD assessment, both treatment responders and non-responders showed better performances in the delayed assessment. Post hoc comparison found significant differences in each time point between the two groups.
conclusionsThese results emphasize the key role of performing multiple assessments post CSF drainage, as response can be more prominent in a delayed rather than an early phase.
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