Evidence map›Paper›PMID 40087727›Full record

Trial reportAdvances in rheumatology (London, England)2025

Health-related quality of life significantly improved in obese patients with psoriatic arthritis one year after a structured weight loss intervention.

Anton J Landgren, Annelie Bilberg, Björn Eliasson, Linda Torres, Mats Dehlin, Lennart T H Jacobsson, Ingrid Larsson, Eva Klingberg

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Advances in rheumatology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02917434 (Effects of Weight-loss Treatment in Obese Patients With Psoriatic Arthritis), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02917434 nacompletednot on this map

Effects of Weight-loss Treatment in Obese Patients With Psoriatic Arthritis

TypeinterventionalSponsorVastra Gotaland RegionRan2016 to 2021Enrolled90ConditionsObesity, Psoriatic Arthritis, Metabolic Syndrome, PsoriasisArmsVery Low Energy Diet (VLED)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anton J LandgrenDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. anton.landgren@rheuma.gu.se.ORCID 0000-0001-7922-3335
Annelie BilbergInstitute of Neuroscience and Physiology, Section of Health and Rehabilitation, Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-1822-0285
Björn EliassonDepartment of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Linda TorresDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mats DehlinDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-5165-0968
Lennart T H JacobssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-4402-148X
Ingrid LarssonDepartment of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Eva KlingbergDepartment of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-6858-6413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this interventional weight loss study, health-related quality of life (HRQoL), anxiety, depression and fatigue were compared at baseline (BL) and at 12 months (M12) in patients with psoriatic arthritis (PsA) and controls.

methodsPsA patients (n = 39) between 25 and 75 years of age, with body mass index (BMI) ≥ 33 kg/m

resultsIn PsA patients, physical HRQoL, as demonstrated by the physical component summary (PCS) of SF-36, improved from median (IQR) 34 (25-45) at BL to 43 (34-50) at M12, p = 0.009. No significant effect on mental HRQoL, demonstrated by the mental component summary (MCS) score, was seen. Similarly in controls, PCS significantly improved (median IQR, 44 (36-50) at BL to 52 (44-55) at M12, p < 0.001), whereas no significant improvement was seen in MCS. Anxiety and depression decreased significantly in both PsA patients and controls.

conclusionsThe weight loss intervention was associated with significant improvements in physical HRQoL, as well as anxiety and depression, in PsA patients and controls.

trial registrationClinicalTrials.gov identifier: NCT02917434, registered on September 21, 2016, retrospectively registered.

Indexed as

Arthritis, PsoriaticObesityQuality of LifeWeight LossWeight Reduction ProgramsAdultAgedAnxietyBody Mass IndexDepressionFatigueFemaleHumansMaleMiddle AgedTreatment OutcomeArthritisHealth-related quality of lifeObesityPsoriatic arthritis

Identifiers

PMID40087727
PMCPMC13488786

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.