Evidence map›Paper›PMID 40087714›Full record

ArticleInternational journal of retina and vitreous2025

Remote web-based self-assessment of visual acuity versus ETDRS in patients with macular diseases: a method comparison study.

Casper van der Zee, Leon Daniel Huang Huynh, Saskia Marijke Imhof, Jeannette Ossewaarde-van Norel, Redmer van Leeuwen, Robert Pieter Leendert Wisse

Abstract readLetter
In one paragraph

Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Casper van der ZeeOphthalmology Department, University Medical Center Utrecht, Utrecht, the Netherlands. c.vanderzee-3@umcutrecht.nl.
Leon Daniel Huang HuynhOphthalmology Department, University Medical Center Utrecht, Utrecht, the Netherlands.
Saskia Marijke ImhofOphthalmology Department, University Medical Center Utrecht, Utrecht, the Netherlands.
Jeannette Ossewaarde-van NorelOphthalmology Department, University Medical Center Utrecht, Utrecht, the Netherlands.
Redmer van LeeuwenOphthalmology Department, University Medical Center Utrecht, Utrecht, the Netherlands.
Robert Pieter Leendert WisseOphthalmology Department, University Medical Center Utrecht, Utrecht, the Netherlands.

Funding

Dr. F.P. Fischer-Stichting FS2021-1
6 · The paper itself

Abstract

backgroundMacular diseases (MD) lead to frequent clinic visits, involve time-consuming visual acuity (VA) measurements by professionals. Independent home measurements could improve efficiency. This study evaluates the agreement of a web-based test in MD compared to in-hospital measurements.

methodsAdults with MD were included at the University Medical Center Utrecht in March-July 2023. Users need a phone, computer, and 3m distance. The test uses Tumbling-E and triangles as optotypes. Primary outcome is the web-based vs. ETDRS Distance Visual Acuity (DVA). Secondary outcomes were test-retest variability (TRV), near visual acuity (NVA), and the Amsler grid. Outcomes were reported in mean differences and 95% Limits of Agreement (LoA).

results89 eyes were included. The DVA mean difference was 0.03LogMAR(1.5 letters), SD0.17, LoA - 0.31;0.36LogMAR(-15.5;18 letters), TRV had a mean difference of 0.03(1.5 letters) SD0.14. The NVA mean difference was 0.13(6.5 letter) SD0.24, positive- and negative predictive values 0.93(95%CI = 0.82;0.98) and 0.71(95%CI = 0.51;0.86) respectively.

conclusionsThe agreement of the DVA web-based test is on par with Snellen line assessment and subpar to ETDRS. We showed that elderly can perform this test independently at home, providing a time- and cost-saving opportunity. Developments should focus on the NVA since it can be a valuable adjunct to MD follow-up.

trial registrationthe Dutch Medical Ethical committee (Medisch Ethische Toetsingscommissie; METC NedMec) registration number: 22-879/DB. Approved at 27-09-2022.

Indexed as

eHealthMacular diseasesOnline eye testingOphthalmologyRemote eye careRetinaTelemedicineTelemonitoringVisual acuity

Identifiers

PMID40087714
PMCPMC11907903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.