Evidence map›Paper›PMID 40087706›Full record

ArticleBMC pharmacology & toxicology2025

A new RP-HPLC approach for estimation of potential impurities of Fosamprenavir - method development and validation.

Ramreddy Godela, Vinod Kumar Nelson, Mohana Vamsi Nuli, Pavan Kumar Jaini, Shilpi Pathak, Krishnaphanisri Ponnekanti, Punna Rao Suryadevara, Gowri Sankararao Burle, Vinyas Mayasa, Kavindra Kumar Kesari

Abstract readValidation Study
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In one paragraph

Article in BMC pharmacology & toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ramreddy Godela *GITAM School of Pharmacy, GITAM Deemed to be University, Hyderabad, Sangareddy, India.
Vinod Kumar Nelson *Unit of Natural Products and Drug Discovery, Centre for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, India. Vinod.kumar457@gmail.com.ORCID 0000-0002-1423-2502
Mohana Vamsi NuliRaghavendra Institute of Pharmaceutical Education and Research, Anantapur, India.
Pavan Kumar JainiRaffles University, Neemrana, Rajasthan, India.
Shilpi PathakInstitute of Pharmaceutical Research, GLA University, Mathura, India.
Krishnaphanisri PonnekantiMalla Reddy Institute of Pharmaceutical Sciences, Maisammaguda, Dulapally, Medchal, India.
Punna Rao SuryadevaraFaculty of Pharmacy, Lincoln University College, Petaling, Malaysia.
Gowri Sankararao BurleDepartment of Chemistry, Lincoln University College, Petaling, Malaysia.
Vinyas MayasaGITAM School of Pharmacy, GITAM Deemed to be University, Hyderabad, Sangareddy, India.
Kavindra Kumar KesariDepartment of Applied Physics, School of Science, Aalto University, Espoo, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current work aims to develop a reliable and robust RP-HPLC method for analyzing Fosamprenavir and its potential impurities, including isomer, amino, propyl, nitro, and Amprenavir. The method used a Zobrax C18 column with a mobile phase of 0.1% V/V orthophosphoric acid in water and acetonitrile in gradient elution at a flow rate of 1 mL/min to accomplish efficient separation with detection at 264 nm and column temperature of 30 ± 2

Indexed as

CarbamatesDrug ContaminationOrganophosphatesSulfonamidesChromatography, High Pressure LiquidChromatography, Reverse-PhaseFuransReproducibility of ResultsCarbamatesfosamprenavirFuransOrganophosphatesSulfonamidesFosamprenavirGradient elutionLinearityPotential impuritiesSensitivity

Identifiers

PMID40087706
PMCPMC11907861

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.