Evidence map›Paper›PMID 40087676›Full record

ArticleJournal of animal science and biotechnology2025

Impacts of zinc caproate supplementation on growth performance, intestinal health, anti-inflammatory activity, and Zn homeostasis in weaned piglets challenged with Escherichia coli K88.

Jilong Xu, Hanzhen Qiao, Liping Gan, Peng Wang, Yifeng Zhao, Zetian Lei, Yixuan Chou, Chenrui Hou, Mengqi Li, Jinrong Wang

Abstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jilong Xu *College of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Hanzhen Qiao *College of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Liping GanCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Peng WangCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Yifeng ZhaoCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Zetian LeiCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Yixuan ChouCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Chenrui HouCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Mengqi LiCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China.
Jinrong WangCollege of Bioengineering, Henan University of Technology, Lianhua Street 100, Zhengzhou, 450001, China. wangjr@haut.edu.cn.

Funding

Cultivation Programme for Young Backbone Teachers in Henan University of Technology 21421204Innovation Fund of Henan University of Technology 2020ZKCJ25National Key Research and Development Program of China 2021YFD1300300
6 · The paper itself

Abstract

backgroundEnterotoxigenic Escherichia coli (ETEC) is one of the primary causes of diarrhea in piglets, creating substantial economic losses in the swine farming industry worldwide. This study aimed to investigate the impacts of zinc caproate (ZnCA, C

resultsThe addition of 1,600 mg/kg ZnCA to the diet of post-weaning piglets effectively enhanced growth performance and nutrient digestibility and reduced the incidence of diarrhea and inflammatory reactions caused by ETEC K88 infection. These therapeutic effects were comparable to those of pharmacological doses of ZnO. In terms of improving intestinal health and Zn homeostasis in post-weaning piglets challenged with ETEC K88, the effectiveness of 1,600 mg/kg ZnCA surpassed that of pharmacological doses of ZnO.

conclusionsOverall, under the experimental conditions of this study, ZnCA exhibited the potential to reduce the pharmacological dosage of ZnO while improving intestinal health and Zn homeostasis in weaned piglets.

Indexed as

AGPsETEC K88Pharmacological doses of ZnOWeaned pigsZnCA

Identifiers

PMID40087676
PMCPMC11908000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.