Evidence map›Paper›PMID 40087574›Full record

ArticleBMC infectious diseases2025

The role of high dose corticosteroid (methylperednisolone pulse therapy) in treatment of multi-organ involvement after bacterial pneumonia and pleural empyema; "case series".

Seyed Hossein Mirlohi, Sanaz Tajfirooz, Mitra Rouhi

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seyed Hossein MirlohiPediatric Respiratory and Sleep Medicine Research Center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. sh.mirlohi2004@gmail.com.
Sanaz TajfiroozChildren's Medical Center, Pediatric Center of Excellence, Tehran, Iran.
Mitra RouhiChildren's Medical Center, Pediatric Center of Excellence, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parapneumonic effusions and empyema usually occur after bacterial pneumonia. Inflammation plays an essential role in the occurrence of pneumonia and can lead to an autoinflammatory condition. In this study, we will present three cases including multi-organ involvement following pleural empyema that have been treated with pulse corticosteroid therapy. Apparently, pleural empyema can lead to multi-organ involvement due to underlying inflammatory processes. This condition is usually associated with symptoms and changes in laboratory parameters that manifest after empyema treatment or reappear after temporary recovery. Hence, managing this condition by pulse corticosteroid therapy can result in positive outcomes.

Indexed as

Adrenal Cortex HormonesEmpyema, PleuralMethylprednisolonePneumonia, BacterialAdultAgedFemaleHumansMaleMiddle AgedTreatment OutcomeAdrenal Cortex HormonesMethylprednisoloneChest tubeEmpyemaMethylprednisolonePleural effusionTissue plasminogen activator

Identifiers

PMID40087574
PMCPMC11907940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.