Evidence map›Paper›PMID 40087517›Full record

ArticleNature medicine2025

Extreme geographic misalignment of healthcare resources and HIV treatment deserts in Malawi.

Joan Ponce, Justin T Okano, Andrea Low, Luckson Dullie, Wongani Mzumara, Sally Blower

Abstract read
In one paragraph

Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joan PonceCenter for Biomedical Modeling, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Justin T OkanoCenter for Biomedical Modeling, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-2476-9370
Andrea LowICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, USA.
Luckson DulliePartners In Health/Abwenzi Pa Za Umoyo, Neno, Malawi.
Wongani MzumaraDepartment of HIV and AIDS, Ministry of Health Malawi, Lilongwe, Malawi.
Sally BlowerCenter for Biomedical Modeling, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. sblower@mednet.ucla.edu.ORCID http://orcid.org/0000-0003-4342-3911

Funding

Using geospatial science to maximize the opportunity to access ART in AfricaR01AI167713 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BLOWER, SALLY MARGARET · 2022 to 2024
$2.5M
NIAID NIH HHS R01 AI167713
6 · The paper itself

Abstract

The Joint United Nations Programme on HIV and AIDS has proposed that human rights should be at the center of efforts to end the HIV pandemic and achieving equity in access to antiretroviral therapy (ART) and HIV healthcare is essential. Here we present a geospatial and geostatistical modeling framework for conducting, at the national level, an equity evaluation of access to ART. We apply our framework to Malawi, where HIV prevalence is ~9%. Access depends upon the number of available healthcare facilities (HCFs), the travel times needed to reach these HCFs, the mode of transportation used (walking, biking, driving) and the supply-to-demand ratio for ART at the HCFs. We find extreme inequities in access to ART. Access maps show striking geographic patterns, revealing clusters of communities with very low or high levels of access. We discover that an extreme geographic misalignment of healthcare resources with respect to need has generated a new type of medical desert: an HIV treatment desert. Around 23% of people living with HIV reside in deserts where they have to walk up to 3 h to reach HCFs; in 2020, these HCFs only received 3% of the national supply of ART. We recommend strategies for shrinking deserts; if not implemented, deserts will grow in size and number.

Indexed as

Health ResourcesHealth Services AccessibilityHIV InfectionsAnti-HIV AgentsAnti-Retroviral AgentsHumansMalawiAnti-HIV AgentsAnti-Retroviral Agents

Identifiers

PMID40087517
PMCPMC12092277

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.