Evidence map›Paper›PMID 40087271›Full record

ArticleNature communications2025

Cholecystokinin neurons in the spinal trigeminal nucleus interpolaris regulate mechanically evoked predatory hunting in male mice.

Dandan Geng, Yaning Li, Bo Yang, Li Zhang, Huating Gu, Tianyun Zhang, Zijie Zhao, Hui Liu, Qingzhuo Cui, Rong Zheng and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dandan Geng *Key Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Yaning Li *Key Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Bo Yang *Key Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Li ZhangNational Institute of Biological Sciences, Beijing, China.
Huating GuNational Institute of Biological Sciences, Beijing, China.
Tianyun ZhangKey Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Zijie ZhaoKey Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Hui LiuKey Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Qingzhuo CuiKey Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Rong ZhengKey Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China.
Peng CaoNational Institute of Biological Sciences, Beijing, China. caopeng@nibs.ac.cn.ORCID http://orcid.org/0000-0001-7739-6857
Fan ZhangKey Laboratory of Neural and Vascular Biology, Ministry of Education; The Key Laboratory of Vascular Biology of Hebei Province; Hebei Medical University, Shijiazhuang, China. zhangfan86@hebmu.edu.cn.ORCID http://orcid.org/0000-0003-0458-6742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predatory hunting plays a critical role in animal survival. Motion-related vibrissal somatosensory signaling is essential for prey detection and hunting in mice. However, little is known about the neural circuits that convert vibrissal somatosensory cues to trigger predatory hunting. Here, we report that mechanical force onto the vibrissal area of the male mice is a key stimulus for predatory hunting. Mechanically evoked predatory hunting was abrogated by the chemogenetic inactivation of cholecystokinin-positive (Cck

Indexed as

CholecystokininNeuronsPredatory BehaviorTrigeminal Nucleus, SpinalAnimalsMaleMiceMice, Inbred C57BLSuperior ColliculiVibrissaeCholecystokinin

Identifiers

PMID40087271
PMCPMC11909130

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.