Evidence map›Paper›PMID 40087214›Full record

ArticleAnnals of nuclear medicine2025

Pulmonary blood flow quantification in humans from 15O-water PET.

Oona Rainio, Henri Kärpijoki, Juhani Knuuti, Riku Klén

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Organ-Specific Perfusion Response to Adenosine as Measured Using Total-Body PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oona RainioTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland. ormrai@utu.fi.ORCID http://orcid.org/0000-0002-7775-7656
Henri KärpijokiTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Juhani KnuutiTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0003-3156-9593
Riku KlénTurku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0002-0982-8360

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDynamic positron emission tomography (PET) imaging has commonly been applied to study blood perfusion in the human brain and heart, but there is a very limited amount of existing research about the suitability of this method for many other organs of interest. Here, we focus on the quantification of pulmonary blood flow (PBF) in human lungs. We evaluate both the potential of the PROCEDURES: We systematically fit the one-tissue compartment model to the mean time-activity curves derived from the

resultsThe estimated PBF within all the lung lobes had a mean of1.21±0.825 mL/min/cm

conclusionsThe PBF quantification based on

Indexed as

LungOxygen RadioisotopesPositron-Emission TomographyPulmonary CirculationWaterAdultAgedAged, 80 and overFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedYoung AdultOxygen-15Oxygen RadioisotopesWater15O-water positron emission tomographyCompartmental modellingDynamic positron emission tomographyPulmonary blood flow

Identifiers

PMID40087214
PMCPMC12095458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.