Evidence map›Paper›PMID 40087180›Full record

ArticleSurgical endoscopy2025

Unsedated emergent ERCP is feasible and efficient for acute cholangitis in old patients over 80 years.

Jia-Qi Xu, Yi-Fan Qu, Zhao-Chao Zhang, Shi-Yao Chen, Yun-Shi Zhong, Yi-Qun Zhang, Wei-Feng Chen, Jian-Wei Hu, Ming-Yan Cai, Li-Qing Yao and 2 more

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Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jia-Qi Xu *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Yi-Fan Qu *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhao-Chao Zhang *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Shi-Yao ChenEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Yun-Shi ZhongEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Yi-Qun ZhangEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Wei-Feng ChenEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Jian-Wei HuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Ming-Yan CaiEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Li-Qing YaoEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Quan-Lin LiEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China. li.quanlin@zs-hospital.sh.cn.
Ping-Hong ZhouEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China. zhou.pinghong@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0002-5434-0540

Funding

Major Project of Shanghai Municipal Science and Technology Committee 19441905200Natural Science Foundation of China 82170555Natural Science Foundation of China 82200600Natural Science Foundation of Xiamen Municipality 20221302Shanghai Rising-Star Program 19QA1401900the National Key R&D Program of China 2019YFC1315800
6 · The paper itself

Abstract

backgroundAcute cholangitis in elderly patients poses unique challenges due to comorbidities and frailty, necessitating timely intervention. This study evaluates the feasibility and efficiency of unsedated emergent endoscopic retrograde cholangiopancreatography (ERCP) in patients over 80 years with acute cholangitis.

methodsA retrospective analysis of elderly patients (≥ 80 years) presenting with acute cholangitis who underwent unsedated emergent ERCP between January 2020 and December 2023 was conducted. Data of patients' clinical characteristics, procedural success rates, adverse events, hospital stays, 30-day mortality and 6-month recurrence were collected and analyzed.

resultsOut of 138 elderly patients included, 128 (92.7%) underwent successful unsedated emergent ERCP procedures. 6 patients had ERCP aborted due to patients' intolerance. 5 (3.1%) patients developed mild post-ERCP pancreatitis. The hospital stays were significantly shorter in patients with successful ERCP (6 days (4,8.5) VS 8.5 days (8,11), P = 0.022). 2 patients died after successful ERCP. 29 (22.7%) patients had recurrence within 6 months and univariate logistic regression analysis indicated patients who had concurrent pancreatitis and cholecystitis had less recurrence (OR 0.125, 95% CI 0.016-0.971).

conclusionUnsedated emergent ERCP appears to be a viable option for managing acute cholangitis in elderly patients over 80 years, offering efficient biliary decompression with acceptable safety profiles. Further prospective studies are warranted to validate these findings and optimize management strategies for this vulnerable population.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholangitisAcute DiseaseAged, 80 and overFeasibility StudiesFemaleHumansLength of StayMalePancreatitisRecurrenceRetrospective StudiesTreatment OutcomeAcute cholangitisOld patientsUnsedated emergent ERCP

Identifiers

PMID40087180

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.