ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025
Anaplastic and poorly differentiated thyroid carcinomas at intervention sites: implications of track seeding and the importance of follow-up monitoring- report of two cases.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Incomplete radiofrequency ablation may elicit pro-oncogenic effects in thyroid cancer cells in a xenograft mouse model.Biology direct · 2026Article
- Ectopic thyroid tissue implantation associated with hyperthyroidism after endoscopic thyroidectomy: a case report.Frontiers in surgery · 2026Article
- Integrating Robotic Bilateral Axillo-Breast Approach Thyroidectomy with Molecular Diagnostics and Artificial Intelligence in Thyroid Cancer Care.Biomolecules & therapeutics · 2026Review
- Multimodal spectrum of approach in poorly differentiated thyroid carcinoma (an updated analysis).Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieReview
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Authors and funding
6 authors.
Funding
Abstract
introductionRadiofrequency ablation (RFA) is widely used to treat benign thyroid nodules. While pre-ablation cancer screenings can produce false-negatives, tumor seeding is rare, and aggressive thyroid cancers following RFA have not been reported. We present two cases of potential track seeding after RFA. CASE REPORT: The first patient is a 56-year-old female who developed anaplastic thyroid cancer, while the second is a 61-year-old female diagnosed with poorly differentiated thyroid cancer. Both had a history of RFA for presumed benign nodules, with cancer identified at the intervention sites.
conclusionThese cases highlight the need for thorough pre-treatment biopsy and careful needle handling during RFA. To date, no cases of cancer directly induced by RFA have been reported; therefore, it is likely that thyroid carcinoma coexisted at the time of the procedure or developed afterward. Early detection through regular follow-up could have prevented progression to aggressive disease. This emphasizes the importance of diligent post-procedural monitoring.
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