Evidence map›Paper›PMID 40087155›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Does sagittal alignment after spinal reconstruction following en bloc tumor resection impact revision rate? A preliminary long-term retrospective study.

Riccardo Cecchinato, Domenico Compagnone, Jorrit-Jan Verlaan, Nicolas Dea, Tianyi Niu, Andrea Pezzi, Francesco Langella, Stefano Boriani

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Riccardo CecchinatoIRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Domenico CompagnoneIRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy. compagnone.nico@gmail.com.
Jorrit-Jan VerlaanDepartment of Orthopaedic Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Nicolas DeaDivision of Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, Canada.
Tianyi NiuDepartment of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, USA.
Andrea PezziUniversity of Milan, Milan, Italy.
Francesco LangellaIRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Stefano BorianiIstituto Ortopedico Rizzoli, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate if postoperative sagittal alignment in long spinal fusions after lumbar enbloc resections can affect mechanical failure rates in a long-term follow-up study.

methodsRetrospective study. All patients with more than 2-years follow-up, with complete demographic and oncological data, and with a set of standing x-rays that allowed the measure of sagittal spinopelvic parameters, the difference between the ideal and actual postoperative lumbar lordosis (LLM) and the Pelvic Incidence - Lumbar Lordosis mismatch (PI-LL) were included. Data on complications, revision surgery and causes of revision were analyzed.

resultsA total of 31 patients were included. Mechanical failure was observed in 10 patients (31%), and of these, 7 (22.6%) received revision surgery. Higher postoperative LLM (21.7° vs. 10.8°, p < 0.05) and higher PI-LL (15.3° vs. 2.8°, p < 0.05) values were found in the group that suffered for implant failure or adjacent disease. Moreover, patients who had undergone surgical revision showed higher LLM (23.7° vs. 11.6, p < 0.05), and PI-LL (19.9° vs. 3°, p < 0.05).

conclusionsThe oncological effectiveness of en bloc resections should be combined with a long-term effectiveness and stability of spinal implants, in order to avoid reduction of quality of life due to implant failure and re-hospitalizations for revision surgery. Our study found that for all included patients mechanical failures were strictly correlated with a mismatch between PI and LL. This suggests that the sagittal balance of the spine affects the endurance of surgical implants also in en bloc resection cases.

Indexed as

LordosisLumbar VertebraePlastic Surgery ProceduresReoperationSpinal FusionSpinal NeoplasmsAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesEn bloc resectionMechanical complicationsSagittal balanceSpinal reconstructionSpinal tumor

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.