Evidence map›Paper›PMID 40085820›Full record

Observational studyEuropean heart journal. Acute cardiovascular care2025

Outcomes with mechanical circulatory support devices among patients with mechanical complications of acute myocardial infarction.

Ahmed M Younes, Ahmed K Mahmoud, Ibrahim Kamel, Linus Williams, Ahmed Maraey, Mahmoud Khalil, Ahmed Elzanaty, Rodrigo Bagur, Abdulla A Damluji, Jacqueline E Tamis-Holland and 1 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European heart journal. Acute cardiovascular care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmed M YounesDepartment of Internal Medicine, Riverside Shore Memorial Hospital, Onancock, VA, USA.ORCID 0000-0002-7847-7867
Ahmed K MahmoudSt. Elizabeth Medical Center, Department of Internal Medicine, Boston University, Boston, MA, USA.
Ibrahim KamelSt. Elizabeth Medical Center, Department of Internal Medicine, Boston University, Boston, MA, USA.
Linus WilliamsDepartment of Medicine, Beth Israel Lahey Medical Center, Burlington, MA, USA.
Ahmed MaraeyDepartment of Cardiology, University of Toledo Medical Center, Toledo, OH, USA.ORCID 0000-0002-8991-1104
Mahmoud KhalilDepartment of Cardiology, University of Connecticut Medical Center, Farmington, CT, USA.
Ahmed ElzanatyWake Forest School of Medicine, Department Of Cardiology, Winston Salem, NC, USA.
Rodrigo BagurDivision of Cardiology, Department of Medicine, Western University, London, ON, Canada.
Abdulla A DamlujiDivision of Cardiology, Inova Center of Outcomes Research, Falls Church, VA, USA.
Jacqueline E Tamis-HollandMiller Family Heart, Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.
Islam Y ElgendyDivision of Cardiovascular Medicine, Gill Heart and Vascular Institute, University of Kentucky, 900 S. Limestone St., Lexington, KY 40536, USA.ORCID 0000-0001-9853-7591

Funding

Frailty and Resiliency in Older Adults with Acute Myocardial InfarctionK23HL153771 · NHLBI · INOVA HEALTH CARE SERVICES · PI DAMLUJI, ABDULLA AL · 2020 to 2024
$916k
NHLBI NIH HHS K23 HL153771
6 · The paper itself

Abstract

aimsThe aim of this study is to examine the trends and outcomes of mechanical circulatory support (MCS) device use among patients with mechanical complications of acute myocardial infarction (AMI). METHODS AND

resultsUsing data from the National Inpatient Sample (a large admirative database in the USA) years 2016-20, we identified AMI admissions (ST-elevation and non-ST-elevation myocardial infarction) with mechanical complications (ventricular septal defect, free wall rupture, or papillary muscle rupture). Among 4 450 219 AMI patients, 7025 (0.2%) had a mechanical complication of which 3115 patients (44.3%) received at least one MCS device. There was a rising trend in MCS use (39.3% in 2016 to 48.9% in 2020, Ptrend = 0.02), but there was no corresponding reduction in the incidence of in-hospital mortality (36.9% in 2016 vs. 43.4% in 2020, Ptrend = 0.75). There was no significant difference in in-hospital mortality between those who received MCS vs. those who did not (48.4 vs. 34.5%, respectively).

conclusionIn this large observational analysis of AMI hospitalizations, mechanical complications were rare and associated with very high in-hospital mortality. Although the use of MCS has increased, in-hospital mortality rates remain high even among patients who received MCS. Further investigations are needed to clarify the role of MCS devices among patients with mechanical complications of AMI.

Indexed as

Heart-Assist DevicesHeart Rupture, Post-InfarctionMyocardial InfarctionAgedFemaleHospital MortalityHumansIncidenceMaleMiddle AgedRetrospective StudiesUnited StatesMechanical circulatory support devicesMechanical complicationsMortalityMyocardial infarction

Identifiers

PMID40085820
PMCPMC13030998

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.