Evidence map›Paper›PMID 40085819›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2025

Baseline and 10-year change in the number of ideal cardiovascular health metrics and sudden cardiac death in the community.

Jean-Philippe Empana, Marie-Cecile Perier, Peder Emile Warming, Eloi Marijon, Irene van Valkengoed, Frederik N Ågesen, Eva Prescott, Rezza Jabbari, Rachel E Climie, Petra Elders and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jean-Philippe EmpanaUniversite Paris Cité, Paris Cardiovascular Research Centre, Integrative Epidemiology of Cardiovascular Diseases, Paris, 56 rue Leblanc, 75015 Paris, France.ORCID 0000-0002-1469-7772
Marie-Cecile PerierUniversite Paris Cité, Paris Cardiovascular Research Centre, Integrative Epidemiology of Cardiovascular Diseases, Paris, 56 rue Leblanc, 75015 Paris, France.ORCID 0000-0002-2798-1334
Peder Emile WarmingDepartment of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-0508-2503
Eloi MarijonUniversite Paris Cité, Paris Cardiovascular Research Centre, Integrative Epidemiology of Cardiovascular Diseases, Paris, 56 rue Leblanc, 75015 Paris, France.ORCID 0000-0001-7227-3428
Irene van ValkengoedDepartment of Public and Occupational Health, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.ORCID 0000-0002-9306-7831
Frederik N ÅgesenDepartment of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-1572-7977
Eva PrescottDepartment of Cardiology, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0002-4134-0349
Rezza JabbariDepartment of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-9432-0632
Rachel E ClimieUniversite Paris Cité, Paris Cardiovascular Research Centre, Integrative Epidemiology of Cardiovascular Diseases, Paris, 56 rue Leblanc, 75015 Paris, France.ORCID 0000-0002-7960-360X
Petra EldersDepartment of General Practice, Amsterdam UMC Location Vrije Universiteit Amsterdam, Boelelaan 1117, Amsterdam, The Netherlands.ORCID 0000-0002-5907-7219
Marieke T BlomDepartment of General Practice, Amsterdam UMC Location Vrije Universiteit Amsterdam, Boelelaan 1117, Amsterdam, The Netherlands.ORCID 0000-0002-8088-1105
Peter J SchwartzCenter for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano IRCCS, Via Pier Lombardo 22, Milan 20135, Italy.ORCID 0000-0003-0367-1048
Hanno L TanDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-7905-5818
J Tfelt-HansenDepartment of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-3895-9316
Xavier JouvenUniversite Paris Cité, Paris Cardiovascular Research Centre, Integrative Epidemiology of Cardiovascular Diseases, Paris, 56 rue Leblanc, 75015 Paris, France.

Funding

European Union's Horizon 2020 research and innovation programme ESCAPE-NET 733381PARQ COST-ACTION CA19137
6 · The paper itself

Abstract

aimsAdherence to an ideal cardiovascular health (CVH) might contribute to lower the burden of sudden cardiac death (SCD) in the community. We aimed to examine the association between the number of ideal CVH metrics at baseline and of its change over 10 years with the risk of SCD. METHODS AND

resultsThe Copenhagen City Heart Study is a community-based prospective cohort study. The number of ideal CVH metrics (range 0-6; non-smoking and ideal level of body mass index, physical activity, untreated glucose, untreated systolic blood pressure, and untreated total cholesterol levels) at baseline in 1991-94 and its 10-year change thereof between 1981-83 and 1991-94 were evaluated. Definite SCD was defined as a death occurring within 1 h (eye-witnessed case) or within 24 h (non-eye-witnessed) of symptoms onset, with the presence of confirmed ventricular tachycardia and the exclusion of non-cardiac cause at autopsy. Fine and Gray sub-distribution HRs (sHRs) were calculated to account for competing risk. The study population includes 8837 participants (57% women; mean age 57 years, ±15 years) in 1991-94. After a median follow-up of 22.6 years from 1 January 1993 up to 31 December 2016, 56 definite SCD occurred. The risk of definite SCD decreased gradually with the number of ideal metrics in 1991-94 [sHR = 0.58; 95% confidence interval (CI): 0.44-0.75 per additional ideal metric] and with the change (i.e. improvement) in the number of ideal metrics between 1981-83 and 1991-94 (sHR = 0.68; 0.50-0.93 per change in the number of ideal metrics). Effect size was lower for coronary death, all-cause mortality, and coronary heart disease events.

conclusionAdherence to a higher number of ideal cardiovascular health was related to a substantial lower risk of definite SCD.

Indexed as

Death, Sudden, CardiacHealth Status IndicatorsAdultAgedCohort StudiesHumansLongitudinal StudiesMaleMiddle AgedRisk AssessmentRisk FactorsCohort studyIdeal cardiovascular health metricsLife’s Simple 7Longitudinal cohortsPrimordial preventionSudden cardiac death

Identifiers

PMID40085819
PMCPMC11953004

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.