Evidence map›Paper›PMID 40085771›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2025

Outcomes of ventricular tachycardia ablation facilitated by pre-procedural cardiac imaging-derived scar characterization: a prospective multi-centre international registry.

Diego Penela, Giulio Falasconi, David Soto-Iglesias, Juan Fernández-Armenta, Giulio Zucchelli, Felipe Bisbal, Fatima Zaraket, Etelvino Silva, Matteo Parollo, Alessia Chiara Latini and 10 more

Abstract readMulticenter Study
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Catheter ablation vs. anti-arrhythmic drug therapy for ventricular tachycardia in ischaemic heart disease: a meta-analysis of randomized controlled trials.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Stereotactic radioablation for ventricular tachycardia in patients untreatable by catheter ablation: evidence of efficacy, safety, and impact on coronary arteries.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  7. Article
  8. The Integral Role of Cardiac Imaging in the Electrophysiology Field.The Journal of innovations in cardiac rhythm management · 2025
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Diego PenelaArrhythmology Department, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID 0009-0009-7221-4829
Giulio FalasconiArrhythmology Department, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID 0000-0001-7128-9911
David Soto-IglesiasHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0003-1394-6260
Juan Fernández-ArmentaDepartment of Cardiology, Puerta del Mar University Hospital, Cadiz, Spain.ORCID 0000-0003-1700-6604
Giulio ZucchelliCardiac Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.ORCID 0000-0001-7274-4541
Felipe BisbalHeart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain.ORCID 0000-0002-4843-7063
Fatima ZaraketHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0002-0706-1987
Etelvino SilvaDepartment of Cardiology, Puerta del Mar University Hospital, Cadiz, Spain.ORCID 0000-0001-6825-243X
Matteo ParolloCardiac Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.ORCID 0000-0001-9397-1938
Alessia Chiara LatiniArrhythmology Department, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID 0000-0002-6024-6278
Jose AldereteHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0003-0318-5349
Daniel ViverosHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0002-8317-561X
Aldo BellidoHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.
Dario TurturielloHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0001-9579-5413
Chiara ValerianoHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0002-0130-6218
Paula Franco-OcañaHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0002-6157-058X
Andrea SagliettoHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0001-9475-1507
Pietro FranciaHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0003-0306-7764
Julio Martí-AlmorHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0001-9927-1190
Antonio BerruezoHeart Institute, Teknon Medical Centre, C/ Vilana, 12, 08022, Barcelona, Spain.ORCID 0000-0002-5418-383X

Funding

"Ricerca Corrente" funding from Italian Ministry of Health to IRCCS Humanitas Research Hospital
6 · The paper itself

Abstract

aimsPre-procedural imaging can facilitate scar-related ventricular tachycardia (VT) ablation, although only limited data have been reported. This prospective registry aimed to analyse procedural data and outcomes in a multi-centre setting of a pre-defined VT ablation strategy facilitated by the integration of pre-procedural imaging into the navigation system. METHODS AND

resultsConsecutive patients referred for scar-related left-sided VT ablation were prospectively enrolled at five European tertiary hospitals. Pre-procedural cardiac magnetic resonance (CMR)-derived scar maps and/or multi-detector computed tomography (MDCT)-derived wall thinning maps of the left ventricle (LV) were obtained and integrated into the navigation system. An endocardial or endoepicardial approach was chosen based on the scar distribution at pre-procedural imaging. The decision of performing a detailed electro-anatomical map (EAM) of the LV (image-aided) or to using the pre-procedural imaging for guiding the ablation without obtaining an EAM (image-guided) was left to the physician's discretion. One hundred and seventy-one patients (71% with ischaemic cardiomyopathy) were included. Cardiac magnetic resonance was integrated in 159 (93%), MDCT in 113 (66%), and both in 101 (59%) procedures. Procedure-related complications occurred in 9 (5%) patients. At a mean follow-up of 18 ± 19 months, the overall survival and VT recurrence-free survival were 91 and 74.4%, respectively. There were no significant differences in long-term ablation outcomes based on the type of cardiomyopathy (P = 0.88) or the pre-procedural imaging modality employed (P = 0.33). An image-guided approach appears feasible, safe, and faster, with reduced procedure, radiofrequency, and fluoroscopy times, without compromising efficacy.

conclusionIn a large multi-centre prospective cohort, VT ablation facilitated by pre-procedural imaging is associated with favourable long-term outcomes.

Indexed as

Catheter AblationCicatrixMultidetector Computed TomographyTachycardia, VentricularAgedEuropeFemaleHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsProspective StudiesRecurrenceRegistriesCardiac imagingCardiac magnetic resonanceCatheter ablationMulti-detector computed tomographyStructural heart diseaseSubstrate ablationVentricular tachycardia

Identifiers

PMID40085771
PMCPMC11983391

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.