ArticleScience advances2025
A multimodal defect-rich nanoreactor triggers sono-piezoelectric tandem catalysis and iron metabolism disruption for implant infections.
Abstract read
In one paragraph
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Advances in ultrasound-mediated nanozyme systems in therapeutic applications.Ultrasonics sonochemistry · 2026Review
- Mott-Schottky Interface in BiChemSusChem · 2026Article
- Piezoelectric Nanocoatings on Bio-Interfaces: Microenvironment Remodeling, Biofilm Disruption, and Immunomodulatory Integration.Microorganisms · 2026Review
- Piezoelectric Nanozymes With Acoustically Rejuvenated Catalytic Activities Rewire Lipid Metabolism for Two-Pronged Ferroptotic Therapy.Angewandte Chemie (International ed. in English) · 2026Article
- A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.Bioactive materials · 2026Article
- Research Progress and Translational Perspectives of Piezoelectric Materials in Dental Implant Surface Engineering.Journal of functional biomaterials · 2026Review
- Self-Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Intelligent multimodal-energy-driven piezoelectric antibacterial platforms: From structural control to system-level diagnosis.Materials today. Bio · 2026Review
- Piezoelectric heterojunction/polyetherketoneketone composite with enhanced sonodynamic efficacy and nanozyme activities for anti-infection and encouraging neurovascular ossification.Journal of nanobiotechnology · 2026Article
- Leveraging piezo-augmented copper-induced bacterial death of sub-1 nm CuO-SrTiOJournal of nanobiotechnology · 2026Article
- Occlusion-activated autonomous piezoelectric implants for adaptive prevention of peri-implantitis.Nature communications · 2026Article
- Black phosphorus in theragenerative medicine: a multi-organ perspective on disease modulation and tissue repair.Bioactive materials · 2026Review
- A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration.Exploration (Beijing, China) · 2026Review
- "Electron transport chain interference" strategy of amplified bacterial ferroptosis and defect-engineered nanozyme for diabetic wound healing.Theranostics · 2026Article
- Sequential treatment of infectious bone defects with three dimensional-printed body temperature-responsive shape memory scaffold coated with metal-polyphenol layers.Burns & trauma · 2026Article
- Nanomaterial-Induced Bacterial Ferroptosis-Like Death: A Novel Strategy to Counteract Antimicrobial Resistance.International journal of nanomedicine · 2026Review
- Ferroptosis-Like Death: An Emerging Innovative Antibacterial Strategy.International journal of nanomedicine · 2026Review
- Virulence-Selective Trap-Capture-Kill Antibacterial Nanostructures With Immune-Metabolic Regulation for Treating Implant-Associated Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Ultrasound activated herbal bio-heterojunctions for self-catalytic regulation and bacterial cuproptosis-like death in the treatment of implant infection.Signal transduction and targeted therapy · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Fuyuan ZhengOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0000-0348-2023
Xufeng WanOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0004-6477-5048
Yangming ZhangOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Yan YueOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0003-1226-1646
Qiaochu LiDepartment of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China.
Zhuang ZhangOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Shuoyuan LiOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Hong XuOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Qiang SuDepartment of Orthopedics, Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang 621000, China.ORCID 0000-0003-1433-3407
Xiaoting ChenAnimal Experimental Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Le TongDepartment of Emergency Medicine, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu 610041, China.
Long ZhaoOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Jian CaoOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Xin TangOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Xiao YangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.ORCID 0000-0001-7248-8218
Jiagang WuCollege of Materials Science and Engineering, Sichuan University, Chengdu 610065, China.ORCID 0000-0002-9960-9275
Jian LiOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.
Xiang LvCollege of Materials Science and Engineering, Sichuan University, Chengdu 610065, China.ORCID 0000-0001-6101-7568
Zongke ZhouOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0001-8091-0474
Duan WangOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0001-5487-4414
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tracking and eradicating drug-resistant bacteria are critical for combating implant-associated infections, yet effective antibacterial therapies remain elusive. Herein, we propose an oxygen vacancy-rich (BiFe)
Indexed as
Anti-Bacterial AgentsIronProstheses and ImplantsProsthesis-Related InfectionsAnimalsCatalysisHydrogen PeroxideMiceReactive Oxygen SpeciesTitaniumUltrasonic WavesAnti-Bacterial AgentsHydrogen PeroxideIronReactive Oxygen SpeciesTitanium
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.