Evidence map›Paper›PMID 40085503›Full record

ArticleeLife2025

Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone.

Yan-Xue Li, Xin-Le Kang, Yan-Li Li, Xiao-Pei Wang, Qiao Yan, Jin-Xing Wang, Xiao-Fan Zhao

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. MET goes to the membrane-A new place for the "old" juvenile hormone receptor.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Membrane-localized MET engages PVR to mediate extranuclear juvenile hormone signaling inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. The GPCR A35 regulates fecundity ofFrontiers in insect science · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan-Xue LiShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.ORCID https://orcid.org/0000-0002-4675-4954
Xin-Le KangShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.
Yan-Li LiShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.
Xiao-Pei WangShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.
Qiao YanShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.
Jin-Xing WangShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.ORCID https://orcid.org/0000-0003-0283-3930
Xiao-Fan ZhaoShandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Shandong, China.ORCID https://orcid.org/0000-0003-1809-4730

Funding

National Natural Science Foundation of China 32270507National Natural Science Foundation of China 32330011
6 · The paper itself

Abstract

Juvenile hormone (JH) is important to maintain insect larval status; however, its cell membrane receptor has not been identified. Using the lepidopteran insect

Indexed as

CadherinsInsect ProteinsJuvenile HormonesMothsReceptor, Fibroblast Growth Factor, Type 1Receptor Protein-Tyrosine KinasesAnimalsCell MembraneHEK293 CellsHumansLarvaSignal TransductionCadherinsInsect ProteinsJuvenile HormonesReceptor, Fibroblast Growth Factor, Type 1Receptor Protein-Tyrosine Kinasesagricultural pestdevelopmental biologyLepidopterametamorphosis

Identifiers

PMID40085503
PMCPMC11908783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.