Evidence map›Paper›PMID 40085421›Full record

ArticleSports medicine (Auckland, N.Z.)2025

Why We Must Stop Assuming and Estimating Menstrual Cycle Phases in Laboratory and Field-Based Sport Related Research.

Kirsty Jayne Elliott-Sale, Marco Altini, Patricia Doyle-Baker, Eva Ferrer, Tessa Rose Flood, Rachel Harris, Franco Milko Impellizzeri, Xanne Janse de Jonge, Katrine Okholm Kryger, Gary Lewin and 8 more

Abstract read
In one paragraph

Article in Sports medicine (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kirsty Jayne Elliott-SaleDepartment of Sport and Exercise Sciences, Institute of Sport, Manchester Metropolitan University Institute of Sport, Manchester, M1 7EL, UK. k.elliott-sale@mmu.ac.uk.ORCID 0000-0003-1122-5099
Marco AltiniDepartment of Human Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-5981-4066
Patricia Doyle-BakerHuman Performance Lab, Faculty of Kinesiology, University of Calgary, Calgary, Canada.ORCID 0000-0001-9296-8921
Eva FerrerBarça Innovation Hub, Health & Wellness Area, Barcelona, Spain.ORCID 0000-0002-9716-1577
Tessa Rose FloodDepartment of Sport and Exercise Sciences, Institute of Sport, Manchester Metropolitan University Institute of Sport, Manchester, M1 7EL, UK.ORCID 0000-0001-8897-0957
Rachel HarrisAustralian Institute of Sport, Bruce, ACT, Australia.ORCID 0000-0002-1955-894X
Franco Milko ImpellizzeriSchool of Sport, Exercise and Rehabilitation, Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia.ORCID 0000-0002-1703-2573
Xanne Janse de JongeGriffith Sports Science, School of Health Sciences and Social Work, Griffith University, Gold Coast, QLD, Australia.ORCID 0000-0003-3657-5298
Katrine Okholm KrygerMedical and Anti-Doping Unit, Football Division, UEFA, Nyon, Switzerland.ORCID 0000-0003-0924-6181
Gary LewinArsenal Women's Football Club, London, UK.
Constance M LebrunDepartment of Family Medicine, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0002-7408-4521
Alan McCallArsenal Performance and Research Team, Arsenal Football Club, London, UK.ORCID 0000-0003-3780-8153
Sophia NimphiusSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, Australia.ORCID 0000-0002-3524-0245
Stuart M PhillipsDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-1956-4098
Paul A SwintonSchool of Health Sciences, Robert Gordon University, Aberdeen, UK.ORCID 0000-0001-9663-0696
Madison TaylorSchool of Sport Sciences, UiT The Arctic University of Norway, Tromsø, Norway.ORCID 0009-0000-4241-3004
Evert VerhagenMedical and Anti-Doping Unit, Football Division, UEFA, Nyon, Switzerland.ORCID 0000-0001-9227-8234
Richard James BurdenDepartment of Sport and Exercise Sciences, Institute of Sport, Manchester Metropolitan University Institute of Sport, Manchester, M1 7EL, UK.ORCID 0000-0002-2811-5454

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increased growth, popularity, and media interest in women's sport has led to calls for greater prioritisation of female-specific research and innovation. In response, science and medicine researchers have increased the volume of sport-related studies investigating female-specific matters, such as the menstrual cycle. Whilst the accelerated rate of published studies with female participants is welcome, the emerging trend of using assumed or estimated menstrual cycle phases to characterise ovarian hormone profiles is a significant concern. Replacing direct measurements of key characteristics of the menstrual cycle (e.g. the surge in luteinising hormone prior to ovulation via urine detection and sufficient luteal phase progesterone via blood or saliva sampling) with assumptions or estimates (i.e. no measurements) is proposed to be a pragmatic and convenient way of generating data, particularly in field-based research (i.e. elite athlete environments), where time, resources, and athlete availability are sometimes constrained. Using assumed or estimated phases, however, amounts to guessing the occurrence and timing of ovarian hormone fluctuations and risks potentially significant implications for female athlete health, training, performance, injury, etc., as well as resource deployment. The positive intentions of researchers and scientific journals in this space are not in question. The aim of this Current Opinion is to explain why using assumed or estimated menstrual cycle phases is an approach that has little scientific basis and lacks the rigour and appropriate methodological quality to produce valid and reliable data. In doing so, we provide evidence-based responses to common speculation points and offer recommendations for future research.

Indexed as

Menstrual CycleSportsFemaleHumansLuteinizing HormoneProgesteroneResearch DesignLuteinizing HormoneProgesterone

Identifiers

PMID40085421
PMCPMC12152053

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.