ReviewNeurology and therapy2025
Menopause, Perimenopause, and Migraine: Understanding the Intersections and Implications for Treatment.
Review in Neurology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF).The journal of headache and pain · 2026Pooled it
- Effect of different acupuncture modalities on sex hormone levels in perimenopausal women: a network meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Dopaminergic Dysregulation in Migraine: From Hypothalamic A11 Dysfunction to a Systemic Biobehavioral Phenotype.International journal of molecular sciences · 2026Review
- Complementary and Alternative Medicine in the Management of Perimenopausal Sleep Disturbances: A Scoping Review.Cureus · 2026Review
- Associations Between Type D Personality, Psychological Symptoms, Pain Severity, and Migraine-Related Outcomes in Women with Migraine.Journal of clinical medicine · 2026Article
- Migraine and menopause as converging factors in brain vulnerability: a hypothesis-driven perspective.The journal of headache and pain · 2026Review
- Geriatric Migraine, Geroscience, and Sustainable Development Goals: Bridging Clinical Complexity and Public Health Priorities.Journal of clinical medicine · 2026Review
- Neurologic Complications of Pregnancy and Menopause.Continuum (Minneapolis, Minn.) · 2026Review
- Tinnitus constancy and self-reported severe headache or migraine symptoms in peri- and postmenopausal women: a statistical modeling and machine learning analysis.European journal of medical research · 2025Observational
- Causal effect of coffee consumption on metabolic syndrome in Korean adults: a 2-sample Mendelian randomization study.Nutrition research and practice · 2025Article
- Impact of visceral pain on migraine symptoms in comorbid patients: a retrospective observational study.The journal of headache and pain · 2025Observational
- Migraine triggers and lifestyle modifications: an assessment of patients' awareness and the role of healthcare providers in patient education.The journal of headache and pain · 2025Article
- Personalized Diagnosis and Functional Impact of Vestibular Migraine in Women Aged 20-50: Cross-Sectional Analysis from Neurotology Clinic.Journal of personalized medicine · 2025Article
- From Headache to Heart Health: Investigating the Migraine-Cardiovascular Disease Connection.Neurology and therapy · 2025Review
- Migraine in men - differences in phenotype and treatment patterns: results from the Migraine in Poland cross-sectional national survey.The journal of headache and pain · 2025Article
- Sex differences in patients' referral to a headache unit.Frontiers in neurology · 2025Article
- Evolving care pathways for women with migraine in Italy: results from a national survey.Frontiers in neurologyArticle
- Premenstrual syndrome, premenstrual dysphoric disorder, and coping strategies in women with menstrual migraine.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine affects women three times more often than it does men, and various mechanisms may explain this incidence, including the key role of female sex hormones. Fluctuations in the levels of these hormones and their feedback control regulate the menstrual cycle, pregnancy, puerperium, perimenopause, and menopause. They can influence the occurrence and severity of migraine throughout the reproductive period. Of particular importance seems to be the perimenopausal period, which is associated with an increase in migraine, especially menstrual migraine, which is considered more disabling and less amenable to treatment than non-menstrual attacks. This article reviews the available evidence documenting the relationship between perimenopause, menopause, and migraine and diagnostic considerations in an attempt to determine the management of these periods of a woman's life. Special considerations, future directions, and unmet needs for perimenopausal and menopausal migraine are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.