Evidence map›Paper›PMID 40085218›Full record

ArticleHeart and vessels2025

Overnight stiffness index from finger photoplethysmography in relation to markers of cardiovascular risk and vascular ageing.

Henrik Hellqvist, Hermine Rietz, Ludger Grote, Jan Hedner, Dirk Sommermeyer, Thomas Kahan, Jonas Spaak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart and vessels, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Henrik HellqvistDivision of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden. henrik.hellqvist@ki.se.ORCID http://orcid.org/0009-0004-4367-7692
Hermine RietzDivision of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Ludger GroteDepartment of Internal Medicine and Clinical Nutrition, Center for Sleep and Vigilance Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jan HednerDepartment of Internal Medicine and Clinical Nutrition, Center for Sleep and Vigilance Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Dirk SommermeyerDepartment of Internal Medicine and Clinical Nutrition, Center for Sleep and Vigilance Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Thomas KahanDivision of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Jonas SpaakDivision of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.

Funding

Hjärt-Lungfonden 20180584Hjärt-Lungfonden 20210529The Swedish State 20180815The Swedish State ALFGBG-966283The Swedish State SLL20181049
6 · The paper itself

Abstract

Wearable technology, such as photoplethysmography (PPG), enables easily accessible individual health data with the potential for improved risk assessment. We hypothesized that the overnight stiffness index (OSI), derived from nocturnal finger PPG, could be used to assess cardiovascular risk and vascular ageing. Subjects with confirmed or suspected hypertension (n = 79, 56 males) underwent simultaneous ambulatory blood pressure monitoring (ABPM) and overnight sleep polygraphy with a continuous PPG registration. Overnight PPG-based pulse propagation time was used to calculate OSI. Associations between OSI and markers of cardiovascular risk, blood pressure, and indices of arterial stiffness, as indicators of vascular ageing, were assessed. Subjects were stratified into low and high OSI (according to median, 10.9 m/s). SCORE2/SCORE2-OP and Framingham risk scores were calculated. The high OSI group had higher SCORE2/SCORE2-OP (9.5 [5.5;12.5] vs 5.0 [4.0;6.5]), and OSI correlated with SCORE2/SCORE2-OP and Framingham risk score (r

Indexed as

AgingBlood PressureCardiovascular DiseasesFingersHypertensionPhotoplethysmographyVascular StiffnessAdultAgedBlood Pressure Monitoring, AmbulatoryFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedPulse Wave AnalysisAmbulatory blood pressure monitoringArterial stiffnessCardiovascular riskHypertensionPhotoplethysmographyPulse wave analysis

Identifiers

PMID40085218
PMCPMC12464147

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.