Evidence map›Paper›PMID 40084879›Full record

ArticleAntimicrobial agents and chemotherapy2025

The efficacy of a regimen comprising clarithromycin, clofazimine, and bedaquiline in a mouse model of chronic

Binayak Rimal, Ruth A Howe, Chandra Panthi, Gyanu Lamichhane

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Macrolide-resistantJournal of clinical tuberculosis and other mycobacterial diseases · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Efficacies of sequenced monotherapies ofbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Binayak RimalDivision of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Ruth A HoweDivision of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Chandra PanthiDivision of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Gyanu LamichhaneDivision of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-2214-0114

Funding

A strategy for new regimens to treat pulmonary Mycobacteroides abscessus infectionR01AI155664 · NIAID · JOHNS HOPKINS UNIVERSITY · PI LAMICHHANE, GYANU · 2020 to 2024
$2.1M
NIAID NIH HHS R01 AI155664NIH HHS AI 155664
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsClarithromycinClofazimineDiarylquinolinesMycobacterium aviumMycobacterium avium-intracellulare InfectionAnimalsDisease Models, AnimalDrug Therapy, CombinationFemaleLungMiceMice, Inbred BALB CMicrobial Sensitivity TestsRifabutinAnti-Bacterial AgentsbedaquilineClarithromycinClofazimineDiarylquinolinesRifabutinbedaquilineclarithromycinclofaziminemouse modelMycobacterium avium

Identifiers

PMID40084879
PMCPMC11963545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.