Evidence map›Paper›PMID 40084877›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2025

Insights into effective fatigue reducing interventions in kidney transplant candidates: a scoping review.

Avril J Haanstra, Heleen Maring, Yvonne van der Veen, Evelien E Quint, Maya J Schroevers, Adelita V Ranchor, Stefan P Berger, Evelyn J Finnema, Coby Annema

Abstract readScoping Review
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Avril J HaanstraDepartment of Health Sciences, Section of Nursing Science, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-6019-7322
Heleen MaringDepartment of Health Sciences, Section of Nursing Science, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Yvonne van der VeenDepartment of Health Sciences, Section of Nursing Science, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-5203-7169
Evelien E QuintDepartment of Surgery, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0003-4065-735X
Maya J SchroeversDepartment of Health Sciences, Section of Health Psychology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-8518-9153
Adelita V RanchorDepartment of Health Sciences, Section of Health Psychology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-7048-3771
Stefan P BergerDepartment of Nephrology, Internal Medicine, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0003-2228-4676
Evelyn J FinnemaDepartment of Health Sciences, Section of Nursing Science, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-2837-6144
Coby AnnemaDepartment of Health Sciences, Section of Nursing Science, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-8663-2145

Funding

Dutch Kidney Foundation 20OS008
6 · The paper itself

Abstract

backgroundFatigue is a prevalent and debilitating symptom among kidney transplant candidates (KTCs), significantly affecting their quality of life and overall well-being. Its complexity necessitates a comprehensive approach to manage fatigue in this population. PURPOSE: To explore the effectiveness of nonpharmacological interventions in reducing fatigue in KTCs.

methodsNonpharmacological interventions targeting fatigue in participants aged ≥18 years, who were either on the kidney transplantation waitlist or eligible candidates, were considered. A database search was conducted in PubMed, Embase, PsycINFO, CINAHL, and Web of Science. Results were reported in accordance with the guidelines provided by the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols extension for Scoping Reviews Checklist.

resultsIn total, 67 studies were included. Interventions were divided into manipulative and body-based practices, exercise, mind-body therapies, energy healing, and combined interventions. Thirty-eight studies (76%) demonstrated a significant effect on fatigue, with effect sizes ranging from 0.43 to 4.85. Reflexology, massage therapy, progressive muscle relaxation, and acupressure combined with massage therapy showed the strongest significant intervention effects on fatigue and had the strongest study quality. However, the overall study quality was weak, particularly concerning confounding control, blinding procedures, and withdrawals and dropouts.

conclusionsManipulative and body-based interventions showed the strongest significant effects on fatigue with the highest study quality. These interventions underscore the multifactorial nature of fatigue by targeting both its physical and psychological dimensions. Future high-quality research is needed to determine the optimal strategy for managing fatigue in KTCs.

Indexed as

FatigueKidney TransplantationMind-Body TherapiesHumanschronic kidney diseasecomplementary therapiesexercisefatiguepreoperative carepsychosocial intervention

Identifiers

PMID40084877
PMCPMC11907435

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.