Evidence map›Paper›PMID 40084741›Full record

ArticleJournal of global health2025

Incidence and costs of hospitalisation due to acute respiratory infection in adults aged over 50 years in Jiangsu, China in 2019-23: a real-world medical database analysis of 0.2 million episodes.

Xiaoyu Xu, Ling Guo, Xiao Li, Xin Wang, You Li

Abstract read
In one paragraph

Article in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyu XuDepartment of Epidemiology, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Ling GuoDepartment of Epidemiology, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Xiao LiCentre for Health Economics Research and Modelling Infectious Diseases (CHERMID), University of Antwerp, Antwerp, Belgium.
Xin WangDepartment of Biostatistics, National Vaccine Innovation Platform, School of Public Health, Nanjing Medical University, Nanjing, China.
You LiDepartment of Epidemiology, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute respiratory infection (ARI) poses a significant public health challenge worldwide, particularly among older adults. However, the disease and economic burden of ARI among older adults in China remained sparse. We aimed to estimate the incidence rate and medical cost of hospitalisation due to ARI among adults aged ≥50 years in Jiangsu Province, China. Methods: We analysed medical records of hospitalised episodes due to ARI from January 2019 to May 2023 from a regionally representative medical database. We estimated hospitalisation rates and the proportion of severe cases (intensive care unit admission, mechanical ventilation, or death) by sex, age group, and time period. Total direct medical cost and out-of-pocket cost were estimated in CNY. We analysed factors influencing total costs using a multivariate linear regression model. We further compared the proportion of severe cases and medical cost between those with and without selected comorbidities. Results: A total of 209 632 episodes of ARI hospitalisation were included. Over the study period, annualised ARI hospitalisation rate ranged from 1.07 to 1.83 per 1000 person-years, and varied by age, sex and region. Severe cases accounted for 6.5-10.3%. The median total direct medical cost was CNY 9027 (interquartile range (IQR) = 6118-14 886), of which 22% (IQR = 7-41) was out-of-pocket. Rural residents born a substantial out-of-pocket cost, which was even higher than their average monthly disposable income. Patients with certain comorbidities had higher medical costs despite having a similar or even lower proportion of severe cases. Conclusions: By analysing a large regionally representative medical database, we helped address the knowledge gap in the burden and cost of ARI hospitalisation in China. While highlighting the overall substantial disease burden and cost of ARI, we identified important factors such as age, sex, region, and comorbidity that influence the disease burden and cost of ARI.

Indexed as

Health Care CostsHospitalizationRespiratory Tract InfectionsAcute DiseaseAgedAged, 80 and overChinaCost of IllnessDatabases, FactualFemaleHumansIncidenceMaleMiddle Aged

Identifiers

PMID40084741
PMCPMC11907735

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.