Evidence map›Paper›PMID 40084715›Full record

ArticleJournal of global health2025

Evolution of long COVID over two years in hospitalised and non-hospitalised survivors in Bangladesh: a longitudinal cohort study.

Farzana Afroze, Shohael Mahmud Arafat, Chowdhury Meshkat Ahmed, Baharul Alam, Sayera Banu, Md Zahidul Islam, Mustafa Mahfuz, Firdausi Qadri, Taufiqur Rahman Bhuiyan, Irin Parvin and 10 more

Abstract read
In one paragraph

Article in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Farzana AfrozeNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Shohael Mahmud ArafatDepartment of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Chowdhury Meshkat AhmedDepartment of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Baharul AlamNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Sayera BanuInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Md Zahidul IslamNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mustafa MahfuzNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Firdausi QadriInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Taufiqur Rahman BhuiyanInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Irin ParvinNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mst Mahmuda AckhterNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Farhana IslamNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Monjeline SultanaNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Eva SultanaNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mohammad Ferdous Ur RahamanDepartment of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Abed Hussain KhanDepartment of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Md Nazmul HasanDepartment of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Shahriar AhmedInfectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mohammod Jobayer ChistiNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Tahmeed AhmedNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In developing settings, comparative data on COVID hospitalised survivors (HS) and non-hospitalised survivors (NHS) is scarce. We determined burdens, incidence, evolution, and associated factors of long COVID-19 over two years among these groups. Methods: We conducted a longitudinal cohort study in Dhaka, Bangladesh, and recruited confirmed COVID-19 survivors from December 2020 to May 2021 (previously reported). 346 survivors underwent in-person follow-ups at five, nine, 18 months and two years post-infection. The assessment included long COVID symptoms, cardiorespiratory function, neuropsychiatric conditions, quality of life, and laboratory tests. The outcomes included one or more symptoms and/or signs indicative of long COVID, aligning closely with the World Health Organization definition of post-COVID-19 condition. Results: Of the 346 participants, we included 326 in the analysis. 78% of HS (n/N = 171/219) and 62% of NHS (n/N = 55/89) reported at least one sequela symptom. HS had higher odds of palpitations, headaches, dizziness, sleeping difficulties, brain fog, muscle weakness, joint pain, hypertension, insulin requirement, poor quality of life, and prolonged corrected QT intervals on electrocardiogram compared to NHS at two years (95% confidence interval (CI)>1). Regarding evolution, sequelae-symptoms, neurological outcomes, restrictive spirometry findings, and electrocardiogram abnormalities remained unchanged, although psychiatric sequelae, quality of life, and exercise capacity improved in both groups. Hospital readmission rates significantly increased (P < 0.05). The incidence rates of palpitations, cough, and hypertension were higher in HS compared to NHS (95% CI>1). Two or more vaccine doses decreased the risk of respiratory (adjusted risk ratio (aRR) = 0.76; 95% CI = 0.63-0.91) and psychiatric sequelae (aRR = 0.78; 95% CI = 0.66-0.92) than one or no doses. Conclusions: COVID-19 survivors, particularly HS, experienced a higher burden of persistent symptoms and health issues two years after infection. However, vaccination significantly reduced the risk of respiratory and psychiatric outcomes. These findings highlight the importance of ongoing vaccination programs and the need for targeted rehabilitation services in low-resource settings.

Indexed as

COVID-19HospitalizationSurvivorsAdultBangladeshFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedQuality of LifeSARS-CoV-2

Identifiers

PMID40084715
PMCPMC11907736

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.