Evidence map›Paper›PMID 40084708›Full record

ArticleMolecular medicine reports2025

Effects of natural killer cell‑conditioned medium on UVB‑induced photoaging in human keratinocytes and a human reconstructed skin model.

Jung Ok Lee, Jung Min Lee, Yujin Kim, A Yeon Park, Daewon Yoon, Su Young Kim, Jihye Heo, Seungryel Han, Hyungjin Nam, Hye Jin Shin and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jung Ok Lee *Department of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
Jung Min Lee *Department of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
Yujin KimDepartment of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
A Yeon ParkDepartment of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
Daewon YoonDepartment of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
Su Young KimDepartment of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
Jihye HeoDepartment of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.
Seungryel HanGC Cell Co., Ltd., Yongin, Seoul 16924, Republic of Korea.
Hyungjin NamGC Cell Co., Ltd., Yongin, Seoul 16924, Republic of Korea.
Hye Jin ShinGC Cell Co., Ltd., Yongin, Seoul 16924, Republic of Korea.
Kyeongsoo JeongGreen Cross Wellbeing Co., Ltd., Yongin, Seoul 16950, Republic of Korea.
Minju ImGreen Cross Wellbeing Co., Ltd., Yongin, Seoul 16950, Republic of Korea.
Beom Joon KimDepartment of Dermatology, College of Medicine, Chung‑Ang University, Seoul 06974, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells produce various cytokines, including interleukin (IL)‑1β, IL‑6, IL‑10, IL‑12, interferon γ, tumor necrosis factor α and transforming growth factor β, which are critical in modulating immune responses. NK cell‑conditioned medium (NK‑CdM), rich in cytokines, has potential applications in therapy and healing. The present study aimed to investigate the protective effect of NK‑CdM against ultraviolet B (UVB)‑mediated photoaging using

Indexed as

KeratinocytesKiller Cells, NaturalSkinSkin AgingUltraviolet RaysCatalaseCell LineCulture Media, ConditionedCytokinesFilaggrin ProteinsHaCaT CellsHumansReactive Oxygen SpeciesSuperoxide Dismutase-1CatalaseCulture Media, ConditionedCytokinesFilaggrin ProteinsFLG protein, humanReactive Oxygen SpeciesSuperoxide Dismutase-1hyaluronan synthasenatural killer cellnatural killer cell‑conditioned mediumnuclear factor erythroid 2‑related factor 2reactive oxygen speciesultraviolet B

Identifiers

PMID40084708
PMCPMC11920773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.