ReviewHistology and histopathology2025
Cytoskeleton proteins, the structural basis of T-lymphocyte and TEC restructure during rapid thymus regeneration.
Review in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Thymus regeneration is the main way for humans to combat immune degeneration and immunosenescence. The interesting cycle of thymus degeneration and regeneration achieves the renewal of adaptive immunity, which is crucial for reconstructing cellular immunity. Rapid thymic regeneration is the main renewal mode after various acute stress-induced thymic involutions, such as radiation, immunosuppressants, and starvation. The cytoskeleton is a key regulator of immune response by affecting the structure and function of immune cells. Our team has conducted years of research on rapid thymic regeneration and found that some types of cytoskeletal proteins, such as F-actin/G-actin, the Thymosin β family, ERM (Ezrin/Radixin/Moesin), and WAVE2, play a critical role in the spatial development of thymic epithelial cells (TECs), and finally regulate the regeneration of the thymus by modulating the skeleton of TECs and T lymphocytes. Here, we summarize the current understanding of cytoskeleton proteins and cell restructure of TECs or T lymphocytes and its relationship with the regeneration of the thymus.
Indexed as
Identifiers
40084412What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.