ArticleAmerican journal of cancer research2025
Comparative study between single modality radiotherapy and concurrent chemoradiation for selected patients with early-stage laryngeal cancer.
Article in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Prognostic Value of Impaired Vocal Cord Mobility in T2N0 Glottic Cancer Treated With IMRT.The Laryngoscope · 2026Article
- Global Disparities and Trends in Radiotherapy for Early-Stage Glottic Cancer.Current oncology (Toronto, Ont.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Unfavorable T2 glottic squamous cell carcinoma with impaired vocal cord mobility and/or bulky disease has been a real treatment challenge with high local failure rates. The purpose of this study is to compare the oncological outcome of unfavorable T2 glottic carcinoma in patients treated with radical radiotherapy versus concurrent chemoradiation. This study is a prospective, open label, randomized trial, in which all patients with unfavorable T2 glottic cancer were treated with either single modality radiotherapy using hypofractionation protocol 65.25 Gy (arm A) or concurrent chemoradiation (arm B) between 2019 and 2023. The primary end points were local control and local progression free survival (PFS). Sixty-two patients were recruited in the study. Local control was significantly higher in concurrent chemoradiation (CCRT) group compared to radiotherapy (RT) group. The 3-year local progression free survival rates were significantly higher in CCRT arm (85.5%) compared to RT arm (57.8%) (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.