ReviewCureus2025
Effect of Liners on Pulpal Outcome After Partial Caries Removal in Permanent Teeth: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Three-Year Clinical and Economic Evaluation of Selective Caries Removal and Full Pulpotomy for Extensive Caries: An Exploratory Randomised Controlled Trial.International endodontic journal · 2026Trial
- Comparison of mineral precipitation, elemental release, pH change and cytotoxicity of calcium-silicate cements and an experimental resin-modified glass ionomer cement containing bioactive glass.Biomaterial investigations in dentistry · 2026Article
- A systematic review and meta-analysis evaluating the success of different protective liners after performing selective caries removal.Biomaterial investigations in dentistry · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Partial caries removal reduces the risk of pulp exposure while preserving the tooth structure that is otherwise unnecessarily lost during the cavity preparation. Liners are applied on the dentinal floors to induce the formation of tertiary dentin that effectively blocks the stimuli from reaching the pulp. The present systematic review was conducted to evaluate the effect of liners on pulp vitality after partial caries removal in permanent teeth. This systematic review followed the resources of evidence-based medicine such as the Cochrane Handbook and was conducted as per PRISMA guidelines. The PICOS strategy was designed and included patients with deep carious lesions in permanent teeth with and without application of liner after partial caries removal, with pulp vitality assessment at one year. After applying the inclusion and exclusion criteria, four articles were selected after an initial list of 750 articles. The results of meta-analysis indicated that there was no statistically significant difference between intervention and control groups (OR=1.440; 95% CL= 0.812 to 2.552; P=0.212). According to the Risk of Bias 2 tool, all four studies were classified as "low risk." Certainty of evidence was moderate as per GRADE (Grading of Recommendations, Assessment, Development, and Evaluations). Partial caries removal with and without a liner had similar outcomes on pulp vitality at one year follow up. Role of a liner remains controversial in partial caries removal therapy. On the basis of this systematic review and meta-analysis, it may be inferred that treatment success, as defined by continued pulp vitality, is independent of liner application.
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Registered trials
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