Evidence map›Paper›PMID 40084279›Full record

ReviewEuropean heart journal. Imaging methods and practice2025

Intracardiac flow dynamics in mitral regurgitation: state of the art.

Lorenzo Serio, Riccardo Beccari, Stefano Nistri, Antonella Cecchetto, Gianni Pedrizzetti, Donato Mele

Abstract readReview
In one paragraph

Review in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Hemodynamic Evaluation for Mitral Valve Replacement.Annals of biomedical engineering · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorenzo SerioDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID https://orcid.org/0009-0002-9122-4757
Riccardo BeccariDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID https://orcid.org/0009-0007-8200-1224
Stefano NistriDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.
Antonella CecchettoDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID https://orcid.org/0000-0003-4069-4177
Gianni PedrizzettiDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0003-2886-7653
Donato MeleDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy.ORCID https://orcid.org/0000-0002-2823-4090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracardiac flow dynamics is a complex phenomenon interrelated with cardiac mechanics. Today, it can be evaluated non-invasively using various imaging modalities, including echocardiography, magnetic resonance imaging, and computed tomography. This review explores the effects of mitral regurgitation on blood flow dynamics inside the left ventricular and atrial cavities and emphasizes the disruption of normal flow dynamics caused by mitral regurgitation, leading to turbulent flow and increased energy dissipation. It further examines the consequences of mitral valve repair and replacement, noting that, while repair generally improves intracardiac flow dynamics compared with replacement, residual flow disturbances may persist. Finally, the implications of abnormal intracardiac vorticity on left ventricular wall stress, myocardial remodelling, and thromboembolic risk are discussed.

Indexed as

cardiac vortexintracardiac flow dynamicsmitral regurgitation

Identifiers

PMID40084279
PMCPMC11904890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.