Evidence map›Paper›PMID 40084145›Full record

ArticleFrontiers in endocrinology2025

The value of targeted CXCR4

Yushi Peng, Fangansheng Chen, Rui Yao, Junping Lan, Yinuo Fu, Kaifeng Ye, Zhiqiang Wang, Qianxiu Zhao, Xiaowei Ji, Kang Xia and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Yushi PengDepartment of Nuclear Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Fangansheng ChenDepartment of Nuclear Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Rui YaoDepartment of Nuclear Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Junping LanDepartment of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Yinuo FuThe First School of Clinical Medicine, Wenzhou Medical University, Wenzhou, China.
Kaifeng YeThe First School of Clinical Medicine, Wenzhou Medical University, Wenzhou, China.
Zhiqiang WangDepartment of Nuclear Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Qianxiu ZhaoDepartment of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xiaowei JiDepartment of Nuclear Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Kang XiaDepartment of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Guoqing ZhuDepartment of Interventional Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Kewen ZhengDepartment of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xuemei Gu *Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Kun Tang *Department of Nuclear Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The study aimed to investigate the diagnostic value of Methods: This study enrolled 88 patients with PA or nonfunctional adenoma (NFA) for Results: In 88 patients, 76 were diagnosed with unilateral PA (UPA), 4 were diagnosed with bilateral PA (BPA), and 8 were diagnosed with NFA, resulting in a total of 95 lesions. To identify UPA, visual analysis received a specificity of 94.12% and a sensitivity of 89.74%. The optimal cutoff values for SUV Conclusions: The CXCR4-targeted

Indexed as

HyperaldosteronismPositron Emission Tomography Computed TomographyReceptors, CXCR4AdenomaAdultAgedFemaleFluorine RadioisotopesHumansMaleMiddle AgedRadiopharmaceuticalsCXCR4 protein, humanFluorine RadioisotopesRadiopharmaceuticalsReceptors, CXCR418 F-pentixaforCXCR4PET/CTprimary aldosteronismsubtypingtreatment

Identifiers

PMID40084145
PMCPMC11903271

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.