Evidence map›Paper›PMID 40084143›Full record

ArticleFrontiers in endocrinology2025

Changes in thyroid function after thermal ablation of thyroid nodules.

Song Li, Ming-An Yu, Zhen-Long Zhao, Ying Wei, Li-Li Peng, Yan Li

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
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  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Song LiChina-Japan Friendship Hospital, Beijing, China.
Ming-An YuChina-Japan Friendship Hospital, Beijing, China.
Zhen-Long ZhaoChina-Japan Friendship Hospital, Beijing, China.
Ying WeiChina-Japan Friendship Hospital, Beijing, China.
Li-Li PengChina-Japan Friendship Hospital, Beijing, China.
Yan LiChina-Japan Friendship Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate changes in thyroid function post-thermal ablation (TA) of thyroid nodules and to identify risk factors associated with post-ablation thyroid function abnormalities. Materials and methods: A retrospective analysis of 2,264 cases treated with TA between June 2015 and July 2024 was conducted, including 1,169 benign thyroid nodules (BTNs) and 1,095 papillary thyroid carcinoma (PTC) cases. Thyrotropin (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) levels were measured before treatment and at 1, 3, 6, 9, and 12 months post-ablation. Result: FT3 levels remained significantly reduced at 12 months post-ablation (3.04 ± 0.42 vs. 3.15 ± 0.36 pg/mL; Conclusion: Thermal ablation had a minimal impact on thyroid function. Pre-ablation TSH levels, Hashimoto's thyroiditis, and multiple nodules were risk factors for post-ablation thyroid function abnormalities.

Indexed as

Thyroid Cancer, PapillaryThyroid GlandThyroid NeoplasmsThyroid NoduleAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesThyroid Function TestsThyrotropinThyroxineTriiodothyronineThyrotropinThyroxineTriiodothyroninebenign thyroid nodulespapillary thyroid carcinomathermal ablationthyroid functionthyroid nodules

Identifiers

PMID40084143
PMCPMC11903275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.