SynthesisFrontiers in veterinary science2024
Prevalence of hepatitis E virus in swine in China: a systematic review with meta-analysis (2004-2023).
Synthesis in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence of classical swine fever in domestic pigs: an integrative systematic review and meta-analysis.Tropical animal health and production · 2026Pooled it
- Pan-genomics and multi-omics for deciphering genetic variation and accelerating genetic improvement in ruminant livestock.Functional & integrative genomics · 2026Review
- Probiotic characterization of Ligilactobacillus murinus ZQL11 isolated from healthy dog feces.Veterinary research communications · 2026Article
- Screening of Lipid-Lowering Acid Bacteria from Traditional Koumiss to Develop a New Probiotic Starter Culture.Probiotics and antimicrobial proteins · 2026Article
- Viral RNA detections of enteric pathogens from caprine raw milk in Central Italy.Frontiers in microbiology · 2026Article
- Investigation of Hepatitis E virus seroprevalence in fattening pigs in Taiwan.Frontiers in veterinary science · 2026Article
- Genomic characterization and recombination analysis of hepatitis E virus in humans and swine across Asia: implications for food safety.Frontiers in microbiology · 2026Article
- Lactic acid bacteria: potentials in canine formulas for puppies.Veterinary research communications · 2025Article
- Veterinary Regenerative Medicine: The Evolving Role of Stem Cell-Based Therapies.Stem cell reviews and reports · 2025Review
- Bioinformatics Analysis of the Key lncRNAs of the Viral Response Pathway in HepG2 Expressing Genotype IV Swine Hepatitis E Virus ORF3.Microorganisms · 2025Article
- Isolation, identification and selection of beneficial canine homologous lactic acid bacteria by their potential probiotic characteristics.Veterinary research communications · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Hepatitis E virus (HEV) is a major cause of acute hepatitis in humans and recognized as a zoonotic pathogen, with swine serving as a primary reservoir. Despite substantial research, comprehensive analysis encompassing regional variations and pig growth stages within China, as well as the influence of recent biosecurity measures on HEV prevalence, remains limited. In this study, we aim to assess the prevalence and risk factors associated with swine HEV in China. Methods: A thorough review of HEV infection studies was conducted using six databases: China National Knowledge Infrastructure, Wanfang, Wipro, Centre for Agriculture and Biosciences International, PubMed, and ScienceDirect, covering publications from January 1, 2004 to December 31, 2023. Eighty-seven studies investigating the seroprevalence of swine HEV IgG antibodies and HEV RNA detection rates were included. A rigorous meta-analysis and quality assessment followed. Results: The combined seroprevalence of swine HEV IgG antibodies was 58.0% (95% confidence interval [CI]: 52.0-65.0). The seroprevalence from 2019 to 2023 was lower (27.4, 95% CI: 26.3-28.2) than that in other years. The seroprevalence was higher in sows (67.2, 95% CI: 55.8-78.7) than in suckling, nursery, and fattening pigs. The detection rate of HEV RNA was 13.0% (95% CI: 11.0-15.0), with fattening pigs showing a significantly higher positivity rate (16.9, 95% CI: 13.2-20.7) than sows and suckling pigs. HEV RNA detection was significantly lower in bile (8.3, 95% CI: 6.3-10.3) than in feces and liver. Discussion: This study highlights the widespread presence of HEV in pig farms across China, with prevalence strongly linked to pig growth stage, study year, and sample type. The findings underscore the importance of pig growth stage, sample type, and recent biosecurity measures in controlling HEV prevalence, providing actionable insights for improving biosecurity practices in pig farms.
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