ArticleFrontiers in aging neuroscience2025
Preoperative imaging biomarkers combined with tap test for predicting shunt surgery outcome in idiopathic normal pressure hydrocephalus: a multicenter retrospective study.
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Brain ventricle morphology markers in predicting shunt surgery outcome in idiopathic normal-pressure hydrocephalus.Fluids and barriers of the CNS · 2026Article
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Authors and funding
11 authors.
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Abstract
Objectives: The study aims to investigate the predictive performance of preoperative imaging features combined with tap test for the outcomes of ventriculoperitoneal (VP) shunt in idiopathic normal pressure hydrocephalus (iNPH). Methods: In this multicenter retrospective study, 166 iNPH patients who underwent VP shunt surgery between August 2019 and November 2023 were included. Preoperative clinical characteristics and imaging features were collected. Preoperative clinical assessment and at least 3 months of postoperative follow-up were performed. Multivariable logistic regression, sensitivity, specificity, and the area under the receiver operating characteristic curve (AUC) were used to evaluate predictive performance. Results: Out of 166 total patients, 96 were responders and 70 non-responders. The tap test showed significant difference between two group ( Conclusion: The findings suggest that the imaging features DESH and CA, when combined with the tap test, enhance the prediction of VP shunt outcomes in iNPH patients. Despite the improved predictive capability, further research focusing on innovative biomarkers for VP shunt is warranted.
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