ArticleHeliyon2025
Clay-based magnetite nano carriers for breast cancer treatment: Apoptosis induction and physicochemical properties.
Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer was the most common cancer in women in 157 countries out of 185 in 2022. Therefore, its prognosis and treatment are the concern of many researchers. On the other hand, the synthesis of nanocomposite based on clay and its ability to be used in the field of cancer treatment and drug delivery has always been attractive and is being developed. In this study, the effect of inducing apoptosis based on synthesized magnetite clay-based for introducing a high-potential nano carrier for breast cancer was investigated. Synthesis of nano-carriers was based on three types of modified clay nano colloids) CbNC), magnetite (MNC) and clay-based magnetite nano carriers (MCbNC). The physicochemical properties of the synthesized samples were investigated by Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), dynamic light scattering (DLS), thermal analysis (TGA) and energy X-ray analysis (EDX). Also, flow cytometry and MTT were used to investigate the induction of apoptosis and toxicity, respectively. In this study, the physicochemical properties of the compounds after surface modification were improved compared to other studies, and the MCbNC compound showed anticancer and apoptosis-inducing properties (96 %) at a lower concentration (IC50,500 μM) than the other two compounds.
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