ReviewTheranostics2025
Recent advances in the mechanisms, current treatment status, and application of multifunctional biomaterials for radiation-induced skin injury.
Review in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Biomaterial-based extracellular vesicle delivery systems for wound healing: From fabrication to applications.Bioactive materials · 2026Review
- Spatiotemporal ultrasound-driven piezoelectric electro-NO therapy restores neuro-vascular-immune homeostasis for radiation ulcer repair.Materials today. Bio · 2026Article
- Radiotherapy-Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments.MedComm · 2026Review
- Article
- Chronic Radiation-Induced Wounds: Pathogenesis, Current Therapeutic Strategies, and Emerging Regenerative Approaches.International journal of molecular sciences · 2026Review
- Microenvironment-responsive injectable dynamic hydrogel for sequential antioxidant and tissue regeneration therapy of radiation-induced skin injury.Bioactive materials · 2026Article
- Targeting Post-Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual-Action Approach for Antioxidant and Immune Modulation.Advanced healthcare materials · 2026Article
- Janus nanomotors for topical treatment of radiation-induced dermatitis.Nature communications · 2026Article
- Alginate and Chitosan-Based Hydrogels for the Treatment of Radiation Dermatitis.International wound journal · 2026Review
- A Novel In Vitro Vascularized Dermis Organotypic Model of Acute and Chronic-Like Wounds.Cells · 2026Article
- Advances in the Prevention and Treatment of Radiation Skin Injury: Mechanisms, Pharmacological Interventions, and Applications of Novel Dressings.International journal of nanomedicine · 2026Review
- Reliability of radiotherapist assessment for radiation induced skin-toxicity: investigational study.Frontiers in oncology · 2026Article
- Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems.Regenerative biomaterials · 2026Review
- Nanotechnology for the Treatment of Radiation Dermatitis: Advances and Translational Perspectives.International journal of nanomedicine · 2026Review
- Hydrogel-Based Strategies for the Prevention and Treatment of Radiation-Induced Skin Injury: Progress and Mechanistic Insights.Biomimetics (Basel, Switzerland) · 2025Review
- Tissue Regeneration of Radiation-Induced Skin Damages Using Protein/Polysaccharide-Based Bioengineered Scaffolds and Adipose-Derived Stem Cells: A Review.International journal of molecular sciences · 2025Review
- ADSC-derived exosomes mitigate radiation-induced skin injury by reducing oxidative stress, inflammation and cell death.Frontiers in public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiation-induced skin injury (RISI) is a prevalent complication following nuclear accidents and radiotherapy for tumors. The associated side effects may include erythema, desquamation, ulceration, and in severe cases, necrosis of certain skin tissues. These adverse reactions significantly impact the quality of life for patients and contribute to both psychological distress and economic burdens. However, there is currently no standardized protocol for the treatment and management of RISI. In comparison to traditional pharmaceuticals, the utilization of biomaterials in addressing radiation-induced diseases has garnered increasing attention due to their superior biocompatibility and outstanding functionality. Nevertheless, comprehensive reviews on this topic remain scarce. In this context, this paper systematically elucidates the pathogenesis of RISI, subsequently introducing the clinical manifestations and advancements in treatment for RISI. It emphasizes a comprehensive discussion on the design and innovation of novel biomaterials aimed at treating and protecting against RISI, while also illustrating the mechanisms by which multifunctional biomaterials enhance both treatment efficacy and protective measures for radiation-induced skin conditions. Finally, it addresses the challenges encountered by multifunctional biomaterials in managing radiation-related diseases and outlines potential directions for future research efforts. The objective of this review is to investigate the therapeutic and protective effects of multifunctional biomaterials in relation to radiation-induced skin injury, thereby providing significant reference value for the design and clinical application of innovative materials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.