Evidence map›Paper›PMID 40083849›Full record

ArticleFood chemistry: X2025

Key factors influencing the formation of α-dicarbonyls and dietary advanced glycation end products in bread and commercial bakery products: Impacts of sugar, lipid and gluten protein.

Cheng-Yi Tsai, Kai-Wei Liao, Shih-Min Hsia, Yin-Chieh Tsai, Keng-Jui Lin, Chi-Tang Ho, Wei-Lun Hung

Abstract read
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cheng-Yi TsaiMaster Program in Food Safety, College of Nutrition, Taipei Medical University, 250 Wu-Hsing St., Taipei 11031, Taiwan.
Kai-Wei LiaoSchool of Food Safety, College of Nutrition, Taipei Medical University, 250 Wu-Hsing St., Taipei 11031, Taiwan.
Shih-Min HsiaSchool of Food Safety, College of Nutrition, Taipei Medical University, 250 Wu-Hsing St., Taipei 11031, Taiwan.
Yin-Chieh TsaiSchool of Food Safety, College of Nutrition, Taipei Medical University, 250 Wu-Hsing St., Taipei 11031, Taiwan.
Keng-Jui LinSchool of Food Safety, College of Nutrition, Taipei Medical University, 250 Wu-Hsing St., Taipei 11031, Taiwan.
Chi-Tang HoDepartment of Food Science, Rutgers University, 65 Dudley Rd., New Brunswick, NJ 08901, USA.
Wei-Lun HungSchool of Food Safety, College of Nutrition, Taipei Medical University, 250 Wu-Hsing St., Taipei 11031, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Dicarbonyls and dietary advanced glycation end products (dAGEs) are potentially harmful compounds formed from the Maillard reaction. Bakery products often contain high levels of α-dicarbonyls and dAGEs due to thermal processing. Additionally, the ingredients used in dough might significantly influence the formation of these compounds. Our findings indicated that adding sucrose notably increased the formation of α-dicarbonyls and methylglyoxal-derived dAGEs in bread, while the incorporation of butter and olive oil had negligible effects. In contrast, substituting high-gluten flour with medium- and low-gluten flour reduced the formation of α-dicarbonyls and dAGEs in bread. Furthermore, correlation analyses revealed a significant positive relationship between total dAGEs content and total sugar content in commercial bakery products, with no significant correlation found with total protein and fat content. This study suggests that the sugar content listed on nutrition labels could serve as a practical indicator for estimating dAGE levels in bakery products.

Indexed as

Bakery productsBreadDietary advanced glycation end productsMaillard reactionα-Dicarbonyls

Identifiers

PMID40083849
PMCPMC11905858

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.