ArticleAllergologie select2025
Recommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics: Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (GPA), Austrian Society for Allergology and Immunology (ÖGAI) and the Swiss Society for Allergology and Immunology (SGAI).
Article in Allergologie select, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- [Perioperative antibiotic prophylaxis-current clinical practise in total joint arthroplasty (TJA) in Germany and establishment of an standard operating procedure (SOP) for primary, revision, and tumor TJA].Orthopadie (Heidelberg, Germany) · 2026Article
- Nationwide survey on penicillin allergy delabeling among German healthcare professionals: knowledge, attitudes and perceived barriers.Infection · 2026Article
- Anaphylaxis and Cardiac Arrest Induced by Initial Intravenous Ceftriaxone: A Case Report.The American journal of case reports · 2026Article
- Italian Evidence-Based Clinical Recommendations on the Appropriateness of Prescriptions and Diagnostic Tests in Pediatric Allergology: Focus on Anaphylaxis, Drug Allergy and Hymenoptera Venom Allergy.Journal of clinical medicine · 2026Review
- Cefazolin as an alternative in patients with a history of penicillin or β-lactam antibiotic allergy: A case overview.Allergologie select · 2026Article
- [De-PEN-SAFE: delabeling of the medical history term "penicillin allergy" with oral exposure to amoxicillin : A multicenter prospective research project on the evaluation of allergies to beta-lactam antibiotics].Die Anaesthesiologie · 2025Article
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15 authors.
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Abstract
β-lactam antibiotics (BLAs) are still the antibiotics of first choice for the treatment of many bacterial infections. Treatment with a BLA is often hindered by a suspected allergy, up to 10% of the population report an allergy to penicillin. After allergological evaluation of the suspected allergic reaction to a BLA, most patients show a low probability of a BLA allergy; only in a minority of cases an allergic reaction to the repeated administration of a BLA appear likely in view of the previous history. In > 90% of cases, the suspected BLA allergy can be ruled out by allergy diagnostics. We recommend a risk-stratified approach in the context of an urgent need for BLA, which should enable most patients to receive a BLA therapy. After acute therapy, allergy diagnostics have to be done to clearly prove or reliably rule out a BLA allergy.
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