Evidence map›Paper›PMID 40083779›Full record

ReviewFrontiers in microbiology2025

Recent insights and advances in gut microbiota's influence on host antiviral immunity.

Ying Liu, Danying Yan, Ran Chen, Yingying Zhang, Chuwen Wang, Guoqing Qian

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  6. Host mScientific reports · 2026
    Article
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  9. Molecular and cellular mechanisms of pentadecanoic acid.World journal of biological chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying LiuHealth Science Center, Ningbo University, Ningbo, Zhejiang, China.
Danying YanDepartment of Infectious Diseases, The First Affiliated Hospital, Ningbo University, Ningbo, Zhejiang, China.
Ran ChenCixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yingying ZhangHealth Science Center, Ningbo University, Ningbo, Zhejiang, China.
Chuwen WangDepartment of Infectious Diseases, The First Affiliated Hospital, Ningbo University, Ningbo, Zhejiang, China.
Guoqing QianHealth Science Center, Ningbo University, Ningbo, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A diverse array of microbial organisms colonizes the human body, collectively known as symbiotic microbial communities. Among the various pathogen infections that hosts encounter, viral infections represent one of the most significant public health challenges worldwide. The gut microbiota is considered an important biological barrier against viral infections and may serve as a promising target for adjuvant antiviral therapy. However, the potential impact of symbiotic microbiota on viral infection remains relatively understudied. In this review, we discuss the specific regulatory mechanisms of gut microbiota in antiviral immunity, highlighting recent advances in how gut microbiota regulate the host immune response, produce immune-related molecules, and enhance the host's defense against viruses. Finally, we also discuss the antiviral potential of oral probiotics.

Indexed as

antiviral immunitygut microbiotametabolitesmicrobiomevirome

Identifiers

PMID40083779
PMCPMC11903723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.