Evidence map›Paper›PMID 40083775›Full record

ReviewBioactive materials2025

4D printing polymeric biomaterials for adaptive tissue regeneration.

Zhe Wang, Duo Ma, Juan Liu, Shi Xu, Fang Qiu, Liqiu Hu, Yueming Liu, Changneng Ke, Changshun Ruan

Abstract readReview
In one paragraph

Review in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  6. Prospects of Four-Dimensional Printing of Polymers for Biomedical Engineering.Polymer science & technology (Washington, D.C.) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhe WangDepartment of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Duo MaResearch Center for Human Tissue and Organ Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Juan LiuResearch Center for Human Tissue and Organ Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Shi XuDepartment of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Fang QiuDepartment of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Liqiu HuDepartment of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Yueming LiuDepartment of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Changneng KeDepartment of Burn and Plastic Surgery, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.
Changshun RuanResearch Center for Human Tissue and Organ Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

4D printing polymeric biomaterials can change their morphology or performance in response to stimuli from the external environment, compensating for the shortcomings of traditional 3D-printed static structures. This paper provides a systematic overview of 4D printing polymeric biomaterials for tissue regeneration and provides an in-depth discussion of the principles of these materials, including various smart properties, unique deformation mechanisms under stimulation conditions, and so on. A series of typical polymeric biomaterials and their composites are introduced from structural design and preparation methods, and their applications in tissue regeneration are discussed. Finally, the development prospect of 4D printing polymeric biomaterials is envisioned, aiming to provide innovative ideas and new perspectives for their more efficient and convenient application in tissue regeneration.

Indexed as

4D printingPolymeric biomaterialsTissue regeneration

Identifiers

PMID40083775
PMCPMC11904411

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.