Evidence map›Paper›PMID 40083705›Full record

ArticleInternational journal of biological sciences2025

Targeting ALG3/FOXD1/BNIP3 Axis Prevents Mitophagy and Gemcitabine Resistance of Nasopharyngeal Carcinoma.

Zhanwang Wang, Yi Jin, Dong He, Yuxing Zhu, Mengqing Xiao, Xiaoming Liu, Yaxin Cheng, Ke Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhanwang WangDepartment of Oncology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Yi JinDepartment of Radiation Oncology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Dong HeCentral South University, Changsha, 410013, China.
Yuxing ZhuDepartment of Oncology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Mengqing XiaoDepartment of Oncology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Xiaoming LiuDepartment of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Yaxin ChengDepartment of Oncology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Ke CaoDepartment of Oncology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the specific role and underlying mechanisms of mitophagy may provide therapeutic benefit to patients with nasopharyngeal carcinoma (NPC). Forkhead box D1 (

Indexed as

DeoxycytidineForkhead Transcription FactorsMembrane ProteinsMitophagyNasopharyngeal CarcinomaNasopharyngeal NeoplasmsProto-Oncogene ProteinsCell Line, TumorCell MovementCell ProliferationDrug Resistance, NeoplasmGemcitabineGene Expression Regulation, NeoplasticHumansBNIP3 protein, humanDeoxycytidineForkhead Transcription FactorsGemcitabineMembrane ProteinsProto-Oncogene ProteinsALG3FOXD1GemcitabineMitophagyNasopharyngeal Carcinoma

Identifiers

PMID40083705
PMCPMC11900802

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.