Evidence map›Paper›PMID 40083683›Full record

ArticleInternational journal of biological sciences2025

Dysregulation of N-glycosylation by

Mingyu Zhang, Mengjing Li, Hanzhen Li, Yanling Wan, Shuang Yang, Shuhui Ji, Haobo Zhang, Chao Liu, Gang Lu, Xiaohua Jiang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Deletion of Ybx1 results in germ cell hypoplasia in mouse embryos.The Journal of reproduction and development · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mingyu ZhangInstitute of Women, Children and Reproductive Health, Shandong University, 250012, China.
Mengjing LiInstitute of Women, Children and Reproductive Health, Shandong University, 250012, China.
Hanzhen LiInstitute of Women, Children and Reproductive Health, Shandong University, 250012, China.
Yanling WanInstitute of Women, Children and Reproductive Health, Shandong University, 250012, China.
Shuang YangSchool of Basic Medical Sciences, Shandong University, Jinan 250012, China.
Shuhui JiState Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
Haobo ZhangInstitute of Women, Children and Reproductive Health, Shandong University, 250012, China.
Chao LiuGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China.
Gang LuCUHK-SDU Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, the Chinese University of Hong Kong, Hong Kong, China.
Xiaohua JiangCenter for Reproduction and Genetics, Department of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.
Hongbin LiuInstitute of Women, Children and Reproductive Health, Shandong University, 250012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-glycosylation protein modification plays a crucial regulatory role in numerous biological processes, although their contribution to male reproduction in mammals remains largely undefined. Here, we found that Ribophorin I (RPN1), a subunit of oligosaccharyltransferase complex, is indispensable for spermatogenesis in male germ cells. Germ cell-specific

Indexed as

Endoplasmic Reticulum StressHexosyltransferasesInfertility, MaleMembrane ProteinsSpermatocytesAnimalsApoptosisGlycosylationMaleMeiosisMiceMice, KnockoutSpermatogenesisdolichyl-diphosphooligosaccharide - protein glycotransferaseHexosyltransferasesMembrane Proteinsendoplasmic reticulum stressfertilitymeiosisN-glycosylationRPN1

Identifiers

PMID40083683
PMCPMC11900820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.