Evidence map›Paper›PMID 40083652›Full record

ArticleCardiac failure review2025

Associations of Obesity and Prognostic Nutritional Index on 1-Year Mortality in Patients with Acute Heart Failure.

Mohammed El-Sheikh, Nora Olsen El Caidi, Aginsha Kandiah, Sandra Henriette Tonning, Ida Arentz Taraldsen, Frederik Dencker Wisborg, Ove Andersen, Jens Dahlgaard Hove, Johannes Grand

Abstract read
In one paragraph

Article in Cardiac failure review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammed El-SheikhDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Nora Olsen El CaidiDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Aginsha KandiahDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Sandra Henriette TonningDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Ida Arentz TaraldsenDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Frederik Dencker WisborgDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Ove AndersenDepartment of Clinical Research, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Jens Dahlgaard HoveDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.
Johannes GrandDepartment of Cardiology, Amager and Hvidovre Hospital, Copenhagen University Hospital Hvidovre, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Increased BMI is paradoxically associated with improved survival among patients with acute heart failure (AHF). However, the impact of different nutritional status on this obesity paradox on 1-year mortality is underreported. The prognostic nutritional index is a simple tool to assess nutrition status. Methods: From 10,027 emergency department admissions at the Amager and Hvidovre Hospital, Copenhagen University Hospital in Denmark, all patients with AHF were identified. Patients were categorised by BMI (normal: 18.5-24.9 kg/m Results: Among 383 AHF patients (median age 76 years), 41.3% were malnourished and 58.7% well nourished. In the well-nourished group, obesity was inversely associated with 1-year mortality (adjusted HR 0.48; 95% CI [0.24-0.95]; p=0.035). However, this correlation disappeared in the malnourished group (adjusted HR 1.08; 95% CI [0.59-2.00]; p=0.798). Mortality rates were significantly lower in the well-nourished group among patients with overweight and obesity. Conclusion: Obesity was associated with reduced 1-year mortality only in AHF patients with good nutritional status, while in malnourished patients, obesity was not associated with 1-year mortality. The prognosis in patients with AHF depends on both the presence of obesity and their nutritional status, highlighting the need for nutritional assessment for risk stratification.

Indexed as

body mass indexHeart failuremortalitynutritionobesityprognosisstratification

Identifiers

PMID40083652
PMCPMC11904423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.