ArticleJournal of thoracic disease2025
Psoas muscle index as a novel measure of frailty and predictor of post-operative outcome in octogenarians with non-small cell lung cancer.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: High body mass index (BMI) is a prevalent risk factor in a growing octogenarian population undergoing curative surgery for non-small cell lung cancer (NSCLC). Whilst BMI is paradoxically protective, its correlation with clinical frailty or objective fitness is unclear, due to the discrepancy of the ratio between muscle and adipose tissue. We aim to assess the relationship between sarcopenia and post operative survival and complications. Methods: Demographic and clinical outcome data from octogenarians undergoing resections for primary NSCLC (January 2016-December 2021) was analysed retrospectively. Routine pre-operative positron emission tomography-computed tomography (PET-CT) scan was used to derive psoas muscle index (PMI) (bilateral measurement of cross-sectional psoas muscle area at the level of L3, divided by height-squared) as a measure of sarcopenia. Results: A total of 189 patients were recruited with a mean age 82 years. Median overall survival (OS) was 2.7 Conclusions: Radiologically derived PMI is an easily replicable marker which may be a useful adjunct to BMI in identifying high-risk octogenarians in whom prehabilitation may achieve superior outcomes post-surgery for NSCLC. Additionally, the method we describe avoids additional imaging to derive these measurements and can be safely incorporated into pre-operative imaging protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.