ArticleJournal of thoracic disease2025
Comprehensive analysis of imaging and pathological features in 20 cases of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma: a retrospective study.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Non-gastric mucosa-associated lymphoid tissue lymphomas: a narrative review of pathogenesis, diagnosis, and treatment strategies.Annals of translational medicine · 2025Review
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3 authors.
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Abstract
Background: Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is a rare, indolent subtype of non-Hodgkin lymphoma with distinct radiological and pathological characteristics. Clinically, patients may present with nonspecific symptoms such as cough or dyspnea, and the disease can mimic other pulmonary conditions. High-resolution computed tomography (HRCT) imaging plays a critical role in identifying characteristic lung patterns, such as nodules, consolidation, or ground-glass opacities, which help in differentiating pulmonary MALT lymphoma from other pulmonary disorders. The study aimed to identify clinical characteristics based on the HRCT imaging features and pathological findings in patients with pulmonary MALT lymphoma. Methods: The retrospective study involved 20 confirmed cases of pulmonary MALT lymphoma from a thoracic specialty hospital. Comprehensive data analysis included HRCT imaging characteristics such as tumor size, location, bronchial changes and peritumoral pulmonary interstitial infiltration, as well as pathological features, including cell type, morphology, and immunohistochemistry. Results: HRCT imaging showed a high prevalence of air bronchogram (100%) and bronchiectasis (85%), with tumors predominantly located in the left upper lobe. Pathologically, tumors predominantly exhibited monocytoid and centrocyte-like cells, minimal atypia, and B-cell markers like CD20 and CD3 expression. Surgical resection was the primary treatment modality in 60% of cases, with the rest receiving chemical treatment. Conclusions: Significant features evident in both HRCT imaging and pathological analysis were identified in pulmonary MALT lymphoma cases. These findings are anticipated to play a crucial role in facilitating early diagnosis and determining optimal treatment strategies.
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