Evidence map›Paper›PMID 40083512›Full record

ArticleJournal of thoracic disease2025

Translocated anterior mitral leaflet sparing is a viable treatment option for both degenerative and functional mitral valve disease.

Francesco Nappi, Antonio Salsano, Ibrahim Abdou, Ivancarmine Gambardella, Sanjeet Singh Avtaar Singh, Almothana Alzamil, Victoire Bonnet, Thibaut Schoell, Nicolas Bonnet

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco NappiDepartment of Cardiac Surgery, Centre Cardiologique du Nord, Saint-Denis, France.
Antonio SalsanoDivision of Cardiac Surgery, Ospedale Policlinico San Martino, Genoa, Italy DISC Department, University of Genoa, Genoa, Italy.
Ibrahim AbdouDepartment of Cardiac Surgery, Centre Cardiologique du Nord, Saint-Denis, France.
Ivancarmine GambardellaDepartment of Cardiothoracic Surgery, Weill Cornell Medicine-New York, Presbyterian Medical Center, New York, NY, USA.
Sanjeet Singh Avtaar SinghDepartment of Cardiothoracic Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
Almothana AlzamilDepartment of Cardiac Surgery, Centre Cardiologique du Nord, Saint-Denis, France.
Victoire BonnetFaculty of Medicine, Sorbonne University, Paris, France.
Thibaut SchoellDepartment of Cardiac Surgery, Centre Cardiologique du Nord, Saint-Denis, France.
Nicolas BonnetDepartment of Cardiac Surgery, Centre Cardiologique du Nord, Saint-Denis, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We present a technique for mitral valve (MV) replacement that preserves the anterior mitral leaflet (AML) using complete chordal-sparing mitral valve replacement (CCS-MVR), which maintains the architecture of the left ventricle. This technique is beneficial for patients with functional, degenerative, and infective MV disease who were unable to undergo MV repair. The objective of this study is to ascertain the most efficacious treatment for MV disease. Furthermore, the study will contribute to international guidelines for this procedure and provide data on its efficacy in treating MV disease. Methods: We performed MV replacement surgery on 161 patients, maintaining the integrity of the entire subvalvular chordae tendineae apparatus. Of these cases, 92 (57.1%) were degenerative, 58 (36.0%) were functional, 9 (5.6%) were infective, and 2 (1.2%) were rheumatic. Of the 93 patients with complicated MV disease, massive calcification was observed in 59 cases (36.6%) and mitral annular disjunction (MAD) was observed in 25 cases (15.5%) while endocarditis with posterior annular abscess was observed in 9 cases (5.6%). The anterior leaflet is detached from its connection to the annulus along the entire extent from the posterior commissure to the anterior commissure. In cases of excess tissue, a section of the free edge of the translocated leaflet must be removed. This must preserve a small section of the edge and the entire chordae tendineae unit. A CCS-MVR requires 24 to 28 individual sutures in routine cases. The AML was reinserted using 12 to 14 single sutures in this specific order: posterior annulus, posterior mitral leaflet, AML, and prosthetic valve. Results: The 30-day mortality rate was 8.7%, based on 14 cases. Ten patients, representing 5% of the total, required reoperation after the initial procedure. Out of 140 patients,74 (52.8%) experienced LV reverse remodeling at the six-month follow-up. Female patients exhibited a significantly higher rate of LV reverse remodeling (71% Conclusions: For patients presenting with severely calcified posterior mitral annulus, complicated Barlow disease with MAD, or endocarditis involving the posterior annulus, the AML is consolidated with the posterior mitral leaflet to form a neo-annulus. This procedure is safe and effective for a wide range of simple and complex MV pathologies. Its efficacy is unquestionable. It preserves the complete architecture of the left ventricle, avoiding dilatation and promoting reverse remodeling.

Indexed as

chordal preservationchordal sparingMitral valve (MV)mitral valve replacement (MVR)

Identifiers

PMID40083512
PMCPMC11898336

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.