ArticleFrontiers in pediatrics2025
Caffeine use in preterm neonates: national insights into Turkish NICU practices.
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Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Pharmacological treatment for apnoea of prematurity-the need for an individualised approach.Frontiers in pediatrics · 2025Review
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Authors and funding
79 authors.
Sezin Unal *Division of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Türkiye.
Serdar Beken *Division of Neonatology, Department of Pediatrics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Atakent Hospital, İstanbul, Türkiye.
Deniz Anuk InceDivision of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Türkiye.
Ozden TuranDivision of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Türkiye.
Ayse Korkmaz ToygarDivision of Neonatology, Department of Pediatrics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Atakent Hospital, İstanbul, Türkiye.
Ayse EcevitDivision of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Türkiye.
Abdullah Baris AkcanDivision of Neonatology, Department of Pediatrics, Aydın Adnan Menderes University Faculty of Medicine, Aydın, Türkiye.
Mustafa Ali AkınDivision of Neonatology, Department of Pediatrics, On Dokuz Mayıs University Faculty of Medicine, Samsun, Türkiye.
Selma AktasDivision of Neonatology, Department of Pediatrics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Maslak Hospital, İstanbul, Türkiye.
Nukhet Aladag CiftdemirDivision of Neonatology, Department of Pediatrics, Trakya University Faculty of Medicine, Edirne, Türkiye.
Emel AltuncuDivision of Neonatology, Department of Pediatrics, University of Health Sciences, Kartal Dr Lutfi Kırdar City Hospital, İstanbul, Türkiye.
Huseyin AltunhanDivision of Neonatology, Department of Pediatrics, Necmettin Erbakan University Faculty of Medicine, Konya, Türkiye.
Baran Cengiz ArcagokDivision of Neonatology, Department of Pediatrics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Altunizade Hospital, İstanbul, Türkiye.
Didem ArmangilDivision of Neonatology, Department of Pediatrics, Koru Ankara Hospital, Ankara, Türkiye.
Esra Arun OzerDivision of Neonatology, Department of Pediatrics, İzmir Tınaztepe University Faculty of Medicine, İzmir, Türkiye.
Banu AydınDivision of Neonatology, Department of Pediatrics, Lokman Hekim University Faculty of Medicine, Ankara, Türkiye.
Handan BezirganogluDivision of Neonatology, Department of Pediatrics, Trabzon Kanuni Training and Research Hospital, Trabzon, Türkiye.
Leyla BilginDivision of Neonatology, Department of Pediatrics, İstanbul University İstanbul Faculty of Medicine, İstanbul, Türkiye.
Erhan CalısıcıDivision of Neonatology, Department of Pediatrics, University of Health Sciences Gulhane Faculty of Medicine, Gulhane Training and Research Hospital, Ankara, Türkiye.
Sebnem CalkavurDivision of Neonatology, Department of Pediatrics, University of Health Sciences İzmir Dr. Behcet Uz Pediatric and Pediatric Surgery Training and Research Hospital, İzmir, Türkiye.
Kıymet CelikDivision of Neonatology, Department of Pediatrics, Akdeniz University Faculty of Medicine, Antalya, Türkiye.
Yalcın CelikDivision of Neonatology, Department of Pediatrics, Mersin University Faculty of Medicine, Mersin, Türkiye.
Bilin CetinkayaDivision of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Adana Dr. Turgut Noyan Training and Research Center, Adana, Türkiye.
Merih CetinkayaDivision of Neonatology, Department of Pediatrics, University of Health Sciences, Basaksehir Cam Sakura City Hospital, İstanbul, Türkiye.
Atalay DemirelDivision of Neonatology, Department of Pediatrics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Acıbadem Kadıkoy Sinasi Can Hospital, İstanbul, Türkiye.
Gamze DemirelDivision of Neonatology, Department of Pediatrics, Koc University Faculty of Medicine, Amerikan Hospital, İstanbul, Türkiye.
Nazan Neslihan DoganDivision of Neonatology, Department of Pediatrics, University of Health Sciences Bakırkoy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Türkiye.
Pelin DoğanDivision of Neonatology, Department of Pediatrics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Acıbadem Atasehir Hospital, İstanbul, Türkiye.
Mehtap DurukanDivision of Neonatology, Department of Pediatrics, Mardin Training and Research Hospital, Mardin, Türkiye.
Defne EngurDivision of Neonatology, Department of Pediatrics, University of Health Sciences Tepecik Training and Research Hospital, İzmir, Türkiye.
Tugba Erener ErcanDivision of Neonatology, Department of Pediatrics, Maltepe University Faculty of Medicine, İstanbul, Türkiye.
Zeynel GokmenDivision of Neonatology, Department of Pediatrics, Baskent University Faculty of Medicine, Konya Training and Research Hospital, Konya, Türkiye.
Ipek Guney VaralDivision of Neonatology, Department of Pediatrics, University of Health Sciences Bursa Yuksek İhtisas Training and Research Hospital, Bursa, Türkiye.
Selvi GulasıDivision of Neonatology, Department of Pediatrics, University of Health Sciences Adana Sehir Hospital, Adana, Türkiye.
Ayla GunlemezDivision of Neonatology, Department of Pediatrics, Kocaeli University Faculty of Medicine, Kocaeli, Türkiye.
Tugba GursoyDivision of Neonatology, Department of Pediatrics, Koc University Faculty of Medicine, Koc University Hospital, İstanbul, Türkiye.
Handan Hakyemez ToptanDivision of Neonatology, Department of Pediatrics, Marmara University Faculty of Medicine Pendik Training and Research Hospital, İstanbul, Türkiye.
Serif HamitoğluDivision of Neonatology, Department of Pediatrics, Bursa Medicana Hospital, Bursa, Türkiye.
Fatih IsleyenDivision of Neonatology, Department of Pediatrics, Sanlıurfa Training and Research Hospital, Urfa, Türkiye.
Irem IyigunDivision of Neonatology, Department of Pediatrics, Ordu University Training and Research Hospital, Ordu, Türkiye.
Sebnem KaderDivision of Neonatology, Department of Pediatrics, Kırklareli Training and Research Hospital, Kırlareli, Türkiye.
Dilek KahvecioğluDivision of Neonatology, Department of Pediatrics, University of Health Sciences Ankara Training and Research Hospital, Ankara, Türkiye.
Gozdem KaykıDivision of Neonatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Murat KostuDivision of Neonatology, Department of Pediatrics, University of Health Sciences İstanbul Kanuni Sultan Suleyman Training and Research Hospital, İstanbul, Türkiye.
Dilek KurnazDivision of Neonatology, Department of Pediatrics, İstanbul Haseki Training and Research Hospital, İstanbul, Türkiye.
Tural MammadalıyevDivision of Neonatology, Department of Pediatrics, Gazı University Faculty of Medicine, Ankara, Türkiye.
Ilke Mungan AkinDivision of Neonatology, Department of Pediatrics, University of Health Sciences Umraniye Training and Research Hospital, İstanbul, Türkiye.
Nejat NarlıDivision of Neonatology, Department of Pediatrics, Cukurova University Faculty of Medicine, Adana, Türkiye.
Emel OkuluDivision of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Türkiye.
Nilufer OkurDivision of Neonatology, Department of Pediatrics, University of Health Sciences Gazi Yasargil Training and Research Hospital, Diyarbakır, Türkiye.
Ozgur OlukmanDivision of Neonatology, Department of Pediatrics, İzmir BakırCay University Faculty of Medicine, Ciğli Training and Research Hospital, İzmir, Türkiye.
Fahri OvalıDivision of Neonatology, Department of Pediatrics, İstanbul Medeniyet University Goztepe Prof. Dr. Suleyman YalCın City Hospital, İstanbul, Türkiye.
Beyza OzcanDivision of Neonatology, Department of Pediatrics, University of Health Sciences Konya City Hospital, Konya, Türkiye.
Ahmet OzdemirDivision of Neonatology, Department of Pediatrics, University of Health Sciences Kayseri City Hospital, Kayseri, Türkiye.
Ozmert OzdemirDivision of Neonatology, Department of Pediatrics, Pamukkale University Faculty of Medicine, Denizli, Türkiye.
Hilal OzkanDivision of Neonatology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Türkiye.
Gonca SandalDivision of Neonatology, Department of Pediatrics, Medipol University Faculty of Medicine, Medipol Mega Hospital, İstanbul, Türkiye.
Dilek SarıcıDivision of Neonatology, Department of Pediatrics, University of Health Sciences Ankara Ataturk Sanatoryum Training and Research Hospital, Ankara, Türkiye.
Cansu SivrikayaDivision of Neonatology, Department of Pediatrics, Hatay Training and Research Hospital, Hatay, Türkiye.
Betul Siyah BilginDivision of Neonatology, Department of Pediatrics, University of Health Sciences Ankara Bilkent Sehir Hospital, Ankara, Türkiye.
Saime SundusDivision of Neonatology, Department of Pediatrics, SelCuk University Faculty of Medicine, Konya, Türkiye.
Ozge Surmeli OnayDivision of Neonatology, Department of Pediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Türkiye.
Huseyin SimsekDivision of Neonatology, Department of Pediatrics, University of Health Sciences Mersin City Hospital, Mersin, Türkiye.
Umit Ayse TandırcıoğluDivision of Neonatology, Department of Pediatrics, Kırıkkale University Faculty of Medicine, Kırıkkale, Türkiye.
Sema TanrıverdiDivision of Neonatology, Department of Pediatrics, Manisa Celal Bayar University Faculty of Medicine, Manisa, Türkiye.
Kadir Serafettin TekgunduzDivision of Neonatology, Department of Pediatrics, Ataturk University Faculty of Medicine, Erzurum, Türkiye.
Demet TerekDivision of Neonatology, Department of Pediatrics, Ege University Faculty of Medicine, İzmir, Türkiye.
Gaffari TuncDivision of Neonatology, Department of Pediatrics, Sivas Cumhuriyet University Faculty of Medicine, Sivas, Türkiye.
Turan TuncDivision of Neonatology, Department of Pediatrics, Memorial Atasehir Hospital, İstanbul, Türkiye.
Ercan TutakDivision of Neonatology, Department of Pediatrics, University of Health Sciences Prof. Dr. Cemil Tascıoğlu City Hospital, İstanbul, Türkiye.
Eda TufekcioğluDivision of Neonatology, Department of Pediatrics, University of Health Sciences Ankara Etlik City Hospital, Ankara, Türkiye.
Funda Tuzun ErdoganDivision of Neonatology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, İzmir, Türkiye.
Ersin UluDivision of Neonatology, Department of Pediatrics, İstanbul Universitesi- Cerrahpasa, Cerrahpasa Faculty of Medicine, İstanbul, Türkiye.
Dilek Ulubas IsikDivision of Neonatology, Department of Pediatrics, University of Health Sciences Etlik Zubeyde Hanım Maternal Health Training and Research Hospital, Ankara, Türkiye.
Nurdan UrasDivision of Neonatology, Department of Pediatrics, İstinye University Bahcesehir Liv Hospital, İstanbul, Türkiye.
Sait Ilker UsluDivision of Neonatology, Department of Pediatrics, Demiroğlu Bilim University İstanbul Florence Nightingale Hospital, İstanbul, Türkiye.
Irem UnalDivision of Neonatology, Department of Pediatrics, Sehit Prof. Dr. İlhan Varank Sancaktepe Training and Research Hospital, İstanbul, Türkiye.
Fatma Hilal YılmazDivision of Neonatology, Department of Pediatrics, Dr. Ali Kemal Belviranli Obstetrics and Gynecology Hospital, Konya, Türkiye.
Ariorad MoniriDepartment of Biostatistics, Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, İstanbul, Türkiye.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Caffeine is a proven medication used for the prevention and treatment of apnea in premature infants, offering both short- and long-term benefits. International guidelines provide a range of recommendations regarding the preterm population eligible for caffeine prophylaxis, including the timing, dosage, and duration of treatment. Our national guidelines, published prior to the most recent updates of the international guidelines, recommend the use of caffeine citrate starting from the first day after delivery for preterm infants with a gestational age of <28 weeks. For infants up to 32 weeks, if positive pressure ventilation is required, the decision should be made on an individual basis. This study aims to describe the variability in caffeine usage across neonatal intensive care units in our country. Methods: An online survey was sent to neonatologist who are members of the Turkish Neonatology Society to describe the variability in caffeine usage in neonatal intensive care units in our country. Results: We collected responses from 74 units. Prophylactic caffeine usage was observed as; GA ≤27 Conclusion: The significant differences in caffeine usage characteristics between and within units highlight the need for clear recommendations provided by standardized guidelines.
Indexed as
apnea of prematuritycaffeineguidelineneonatal intensive care unitpremature neonate
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