Evidence map›Paper›PMID 40083428›Full record

ArticleFrontiers in pediatrics2025

Case Report: Anti-interferon-γ autoantibodies in an adolescent with disseminated

Bingkun Li, Tiantian Li, Qihua Huang, Nanfang Mo, Xiaojuan He, Zhiwen Jiang, Xiuying Li, Xiaolu Huang, Xinyu Zhang, Cunwei Cao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. AFrontiers in fungal biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bingkun LiDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Tiantian LiDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Qihua HuangDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Nanfang MoDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xiaojuan HeDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhiwen JiangDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xiuying LiDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xiaolu HuangDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xinyu ZhangDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Cunwei CaoDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anti-interferon-γ autoantibodies (AIGAs) are associated with adult-onset immunodeficiency syndrome, which makes individuals susceptible to intracellular pathogen infections. However, AIGAs are rarely reported in adolescents. Case presentation: We report a 13-year-old Chinese boy who presented with fever, cough, and enlarged cervical lymph nodes. Blood cultures yielded Conclusion: This case highlights the importance of screening for AIGAs in pediatric patients with disseminated TM or NTM infections. Prolonged treatment and continuous follow-up remains crucial for managing pediatric patients with AIGAs.

Indexed as

adolescentsanti-interferon-γ autoantibodiesimmunodeficiency syndromenontuberculous mycobacteriaTalaromyces marneffei

Identifiers

PMID40083428
PMCPMC11903452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.