ArticleJournal of oral biology and craniofacial research
Effects of Roselle (
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Mesenchymal stem cells derived from gingiva normoxic or hypoxic-preconditioning allogenous transplantation affect orthodontic tooth movement in vivo.Journal of dental sciences · 2026Article
- Effects ofJournal of Taibah University Medical Sciences · 2025Article
- Bio-dye-sensitized TiORSC advances · 2025Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Roselle ( Objective: To investigate TNF-α, NF-κB, HSP-10, HSP-70, ALP, and osteocalcin expression after RFE administration during OTM in the AB Materials and methods: Forty healthy male Wistar rats (Rattus norvegicus) were randomly divided into two groups, OTM group (K) and OTM with RFE group (KP). An 8-mm nickel-titanium closed coil spring and a ligature wire linked from the first upper left molar to the central incisor at a light force of 10 g. The rats received RFE administration using a blunt microneedle and a 0.01-ml dosage on the gingiva sulcus of a molar on days 1, 7, 14, and 21 and were then sacrificed, respectively. The ALP, osteocalcin, NFκβ, TNF-α, HSP-10, and HSP-70 expressions were analyzed immunohistochemically. Result: The highest HSP-70, NFκβ, and TNF-α expressions on the compression side of the AB found on day 1 were significantly different between the groups (p ≤ 0.05). The highest expressions of ALP and HSP-10 on the tension side were found on day 7. Meanwhile, the highest osteocalcin expression found on day 21 was significantly different between the groups (p ≤ 0.05). Conclusion: RFE decreased TNF-α, NF-κB, and HSP-70 expression and enhanced osteocalcin and ALP expression in the AB during OTM in Wistar rats (
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